Ge GB - Search Results

1

Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent Pan-Inhibitor Against Gut Microbial Bile Salt Hydrolases.

Xue-Zhang, Li CY, Zhu GH, Song LL, Zhao YW, Ma YH, Ping-Tian, Chen WS, Ge GB. Xue-Zhang, et al. Among authors: ge gb. J Agric Food Chem. 2024 Oct 23;72(42):23233-23245. doi: 10.1021/acs.jafc.4c03617. Epub 2024 Oct 8. J Agric Food Chem. 2024. PMID: 39378230

2

Discovery and characterization of amentoflavone as a naturally occurring inhibitor against the bile salt hydrolase produced by Lactobacillus salivarius.

Li CY, Wang HN, He RJ, Huang J, Song LL, Song YQ, Huo PC, Hou J, Ji G, Ge GB. Li CY, et al. Among authors: ge gb. Food Funct. 2022 Mar 21;13(6):3318-3328. doi: 10.1039/d1fo03277a. Food Funct. 2022. PMID: 35257124

3

Discovery of naturally occurring inhibitors against SARS-CoV-2 3CL^pro from Ginkgo biloba leaves via large-scale screening.

Xiong Y, Zhu GH, Wang HN, Hu Q, Chen LL, Guan XQ, Li HL, Chen HZ, Tang H, Ge GB. Xiong Y, et al. Among authors: ge gb. Fitoterapia. 2021 Jul;152:104909. doi: 10.1016/j.fitote.2021.104909. Epub 2021 Apr 22. Fitoterapia. 2021. PMID: 33894315 Free PMC article.

4

Discovery and Characterization of the Naturally Occurring Inhibitors Against Human Pancreatic Lipase in Ampelopsis grossedentata.

Qin XY, Hou XD, Zhu GH, Xiong Y, Song YQ, Zhu L, Zhao DF, Jia SN, Hou J, Tang H, Ge GB. Qin XY, et al. Among authors: ge gb. Front Nutr. 2022 Feb 25;9:844195. doi: 10.3389/fnut.2022.844195. eCollection 2022. Front Nutr. 2022. PMID: 35284458 Free PMC article.

5

Discovery of the covalent SARS-CoV-2 M^pro inhibitors from antiviral herbs via integrating target-based high-throughput screening and chemoproteomic approaches.

Zhang YN, Zhu GH, Liu W, Chen XX, Xie YY, Xu JR, Jiang MF, Zhuang XY, Zhang WD, Chen HZ, Ge GB. Zhang YN, et al. Among authors: ge gb. J Med Virol. 2023 Nov;95(11):e29208. doi: 10.1002/jmv.29208. J Med Virol. 2023. PMID: 37947293

6

Discovery of a botanical compound as a broad-spectrum inhibitor against gut microbial β-glucuronidases from the Tibetan medicine Rhodiola crenulata.

Chen L, Hou XD, Zhu GH, Huang J, Guo ZB, Zhang YN, Sun JM, Ma LJ, Zhang SD, Hou J, Ge GB. Chen L, et al. Among authors: ge gb. Int J Biol Macromol. 2024 May;267(Pt 1):131150. doi: 10.1016/j.ijbiomac.2024.131150. Epub 2024 Mar 29. Int J Biol Macromol. 2024. PMID: 38556236

7

Discovery and characterization of naturally occurring covalent inhibitors of SARS-CoV-2 M^pro from the antiviral herb Ephedra.

Hu Q, Zhang Y, Chen P, Zhang Y, Zhu G, Liu W, Wang C, Zheng S, Shen N, Wang H, Huang P, Ge G. Hu Q, et al. Chin J Nat Med. 2024 Sep;22(9):797-807. doi: 10.1016/S1875-5364(24)60577-7. Chin J Nat Med. 2024. PMID: 39326974

8

Methylophiopogonanone A is a naturally occurring broad-spectrum inhibitor against human UDP-glucuronosyltransferases: Inhibition behaviours and implication in herb-drug interactions.

Zhou QH, Zhu GH, Song YQ, Que YF, He QQ, Tu DZ, Zeng HR, Qin WW, Ai CZ, Ge GB. Zhou QH, et al. Among authors: ge gb. Basic Clin Pharmacol Toxicol. 2021 Dec;129(6):437-449. doi: 10.1111/bcpt.13651. Epub 2021 Sep 28. Basic Clin Pharmacol Toxicol. 2021. PMID: 34478607 Free article.

9

The SARS-CoV-2 main protease (M^pro): Structure, function, and emerging therapies for COVID-19.

Hu Q, Xiong Y, Zhu GH, Zhang YN, Zhang YW, Huang P, Ge GB. Hu Q, et al. Among authors: ge gb. MedComm (2020). 2022 Jul 14;3(3):e151. doi: 10.1002/mco2.151. eCollection 2022 Sep. MedComm (2020). 2022. PMID: 35845352 Free PMC article. Review.

10

Discovery of 4'-trifluoromethylchalcones as novel, potent and selective hCYP1B1 inhibitors without concomitant AhR activation.

Wu Y, Shi JH, Zhu GH, Xiong Y, Gong JH, Wei HZ, Guo ZB, Dai ZR, Sun XB, Ge GB. Wu Y, et al. Among authors: ge gb. Eur J Med Chem. 2023 Oct 5;258:115552. doi: 10.1016/j.ejmech.2023.115552. Epub 2023 Jun 8. Eur J Med Chem. 2023. PMID: 37315474

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