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Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis.
Wang W, Arreola M, Mathews T, DeVilbiss AW, Zhao Z, Martin-Sandoval M, Mohammed A, Benegiamo G, Awani A, Goeminne LJE, Dever DP, Nakauchi Y, Porteus MH, Pavel-Dinu M, Al Herz W, Auwerx J, Morrison SJ, Weinacht KG. Wang W, et al. Among authors: goeminne lje. Blood. 2024 Oct 8:blood.2024024123. doi: 10.1182/blood.2024024123. Online ahead of print. Blood. 2024. PMID: 39378586
Genetic background and sex control the outcome of high-fat diet feeding in mice.
Bachmann AM, Morel JD, El Alam G, Rodríguez-López S, Imamura de Lima T, Goeminne LJE, Benegiamo G, Loric S, Conti M, Sleiman MB, Auwerx J. Bachmann AM, et al. Among authors: goeminne lje. iScience. 2022 May 25;25(6):104468. doi: 10.1016/j.isci.2022.104468. eCollection 2022 Jun 17. iScience. 2022. PMID: 35677645 Free PMC article.
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression.
Benegiamo G, von Alvensleben GVG, Rodríguez-López S, Goeminne LJE, Bachmann AM, Morel JD, Broeckx E, Ma JY, Carreira V, Youssef SA, Azhar N, Reilly DF, D'Aquino K, Mullican S, Bou-Sleiman M, Auwerx J. Benegiamo G, et al. Among authors: goeminne lje. J Exp Med. 2023 Apr 3;220(4):e20221738. doi: 10.1084/jem.20221738. Epub 2023 Feb 14. J Exp Med. 2023. PMID: 36787127 Free PMC article.
The mouse metallomic landscape of aging and metabolism.
Morel JD, Sauzéat L, Goeminne LJE, Jha P, Williams E, Houtkooper RH, Aebersold R, Auwerx J, Balter V. Morel JD, et al. Among authors: goeminne lje. Nat Commun. 2022 Feb 1;13(1):607. doi: 10.1038/s41467-022-28060-x. Nat Commun. 2022. PMID: 35105883 Free PMC article.
COX7A2L genetic variants determine cardiorespiratory fitness in mice and human.
Benegiamo G, Bou Sleiman M, Wohlwend M, Rodríguez-López S, Goeminne LJE, Laurila PP, Klevjer M, Salonen MK, Lahti J, Jha P, Cogliati S, Enriquez JA, Brumpton BM, Bye A, Eriksson JG, Auwerx J. Benegiamo G, et al. Among authors: goeminne lje. Nat Metab. 2022 Oct;4(10):1336-1351. doi: 10.1038/s42255-022-00655-0. Epub 2022 Oct 17. Nat Metab. 2022. PMID: 36253618 Free PMC article.
Inhibition of sphingolipid de novo synthesis counteracts muscular dystrophy.
Laurila PP, Luan P, Wohlwend M, Zanou N, Crisol B, Imamura de Lima T, Goeminne LJE, Gallart-Ayala H, Shong M, Ivanisevic J, Place N, Auwerx J. Laurila PP, et al. Among authors: goeminne lje. Sci Adv. 2022 Jan 28;8(4):eabh4423. doi: 10.1126/sciadv.abh4423. Epub 2022 Jan 28. Sci Adv. 2022. PMID: 35089797 Free PMC article.
Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction.
Wohlwend M, Laurila PP, Goeminne LJE, Lima T, Daskalaki I, Li X, von Alvensleben G, Crisol B, Mangione R, Gallart-Ayala H, Lalou A, Burri O, Butler S, Morris J, Turner N, Ivanisevic J, Auwerx J. Wohlwend M, et al. Among authors: goeminne lje. Elife. 2024 Mar 20;12:RP90522. doi: 10.7554/eLife.90522. Elife. 2024. PMID: 38506902 Free PMC article.
25 results