Amaral M - Search Results

1

Synthesis of a dehydrodieugenol B derivative as a lead compound for visceral leishmaniasis-mechanism of action and in vivo pharmacokinetic studies.

Amaral M, Romanelli MM, Asiki H, Bicker J, Lage DP, Freitas CS, Taniwaki NN, Lago JHG, Coelho EAF, Falcão A, Fortuna A, Anderson EA, Tempone AG. Amaral M, et al. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0083124. doi: 10.1128/aac.00831-24. Epub 2024 Oct 9. Antimicrob Agents Chemother. 2024. PMID: 39382276 Free PMC article.

2

Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria.

Conserva GAA, da Costa-Silva TA, Amaral M, Antar GM, Neves BJ, Andrade CH, Tempone AG, Lago JHG. Conserva GAA, et al. Among authors: amaral m. Phytomedicine. 2019 Feb 15;54:302-307. doi: 10.1016/j.phymed.2018.09.236. Epub 2018 Oct 9. Phytomedicine. 2019. PMID: 30668381

3

A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division.

Amaral M, de Sousa FS, Silva TAC, Junior AJG, Taniwaki NN, Johns DM, Lago JHG, Anderson EA, Tempone AG. Amaral M, et al. Sci Rep. 2019 Apr 16;9(1):6114. doi: 10.1038/s41598-019-42273-z. Sci Rep. 2019. PMID: 30992481 Free PMC article.

4

Synthesis and Structure-Activity Relationship of Dehydrodieugenol B Neolignans against Trypanosoma cruzi.

Sear CE, Pieper P, Amaral M, Romanelli MM, Costa-Silva TA, Haugland MM, Tate JA, Lago JHG, Tempone AG, Anderson EA. Sear CE, et al. Among authors: amaral m. ACS Infect Dis. 2020 Nov 13;6(11):2872-2878. doi: 10.1021/acsinfecdis.0c00523. Epub 2020 Oct 13. ACS Infect Dis. 2020. PMID: 33047947 Free PMC article.

5

Aporphine Alkaloids from Ocotea puberula with Anti-Trypanosoma Cruzi Potential - Activity of Dicentrine-β-N-Oxide in the Plasma Membrane Electric Potentials.

Barbosa H, Costa-Silva TA, Alves Conserva GA, Araujo AJ, Lordello ALL, Antar GM, Amaral M, Soares MG, Tempone AG, Lago JHG. Barbosa H, et al. Among authors: amaral m. Chem Biodivers. 2021 Apr;18(4):e2001022. doi: 10.1002/cbdv.202001022. Epub 2021 Mar 1. Chem Biodivers. 2021. PMID: 33635585

6

γ-Lactones from Persea americana and Persea fulva - in Vitro and in Silico Evaluation of Trypanosoma cruzi Activity.

Reis IMA, Umehara E, Conceição RS, de M Oliveira L, Coelho Dos S Junior M, Costa-Silva TA, Amaral M, Tempone AG, Branco A, Lago JHG. Reis IMA, et al. Among authors: amaral m. Chem Biodivers. 2021 Sep;18(9):e2100362. doi: 10.1002/cbdv.202100362. Epub 2021 Jul 29. Chem Biodivers. 2021. PMID: 34254435

7

(-)-T-Cadinol-a Sesquiterpene Isolated From Casearia sylvestris (Salicaceae)-Displayed In Vitro Activity and Causes Hyperpolarization of the Membrane Potential of Trypanosoma cruzi.

Dos Santos AL, Amaral M, Hasegawa FR, Lago JHG, Tempone AG, Sartorelli P. Dos Santos AL, et al. Among authors: amaral m. Front Pharmacol. 2021 Nov 3;12:734127. doi: 10.3389/fphar.2021.734127. eCollection 2021. Front Pharmacol. 2021. PMID: 34803682 Free PMC article.

8

Evaluation of antileishmanial potential of the antidepressant escitalopram in Leishmania infantum.

Lima ML, Amaral M, Borborema SET, Tempone AG. Lima ML, et al. Among authors: amaral m. J Pharm Biomed Anal. 2022 Feb 5;209:114469. doi: 10.1016/j.jpba.2021.114469. Epub 2021 Nov 23. J Pharm Biomed Anal. 2022. PMID: 34838348

9

Optimization of physicochemical properties is a strategy to improve drug-likeness associated with activity: Novel active and selective compounds against Trypanosoma cruzi.

Varela MT, Amaral M, Romanelli MM, de Castro Levatti EV, Tempone AG, Fernandes JPS. Varela MT, et al. Among authors: amaral m. Eur J Pharm Sci. 2022 Apr 1;171:106114. doi: 10.1016/j.ejps.2021.106114. Epub 2022 Jan 2. Eur J Pharm Sci. 2022. PMID: 34986415 Free article.

10

Corrigendum: (-)-T-Cadinol, a Sesquiterpene Isolated From Casearia sylvestris (Salicaceae)-Displayed In Vitro Activity and Causes Hyperpolarization of the Membrane Potential of Trypanosoma cruzi.

Dos Santos AL, Amaral M, Hasegawa FR, Lago JHG, Tempone AG, Sartorelli P. Dos Santos AL, et al. Among authors: amaral m. Front Pharmacol. 2022 Mar 14;13:865432. doi: 10.3389/fphar.2022.865432. eCollection 2022. Front Pharmacol. 2022. PMID: 35370638 Free PMC article.

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