Chien WW - Search Results

1

SLC26A4-AP-2 mu2 interaction regulates SLC26A4 plasma membrane abundance in the endolymphatic sac.

Lee HJ, Fenollar-Ferrer C, Isgrig K, Wang YX, Valente K, Eide J, Honda K, Chien WW, Petralia RS, Dong L, Friedman TB, Bonifacino JS, Griffith AJ, Roux I. Lee HJ, et al. Among authors: chien ww. Sci Adv. 2024 Oct 11;10(41):eadm8663. doi: 10.1126/sciadv.adm8663. Epub 2024 Oct 9. Sci Adv. 2024. PMID: 39383236 Free PMC article.

2

Surgical Methods for Inner Ear Gene Delivery in Neonatal Mouse.

Isgrig K, Chien WW. Isgrig K, et al. Among authors: chien ww. Methods Mol Biol. 2019;1937:221-226. doi: 10.1007/978-1-4939-9065-8_13. Methods Mol Biol. 2019. PMID: 30706399 Free PMC article.

3

AAV8BP2 and AAV8 transduce the mammalian cochlear lateral wall and endolymphatic sac with high efficiency.

Isgrig K, Ishibashi Y, Lee HJ, Zhu J, Grati M, Bennett J, Griffith AJ, Roux I, Chien WW. Isgrig K, et al. Among authors: chien ww. Mol Ther Methods Clin Dev. 2022 Jul 31;26:371-383. doi: 10.1016/j.omtm.2022.07.013. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 36034771 Free PMC article.

4

Gene Therapy Restores Hair Cell Stereocilia Morphology in Inner Ears of Deaf Whirler Mice.

Chien WW, Isgrig K, Roy S, Belyantseva IA, Drummond MC, May LA, Fitzgerald TS, Friedman TB, Cunningham LL. Chien WW, et al. Mol Ther. 2016 Feb;24(1):17-25. doi: 10.1038/mt.2015.150. Epub 2015 Aug 26. Mol Ther. 2016. PMID: 26307667 Free PMC article.

5

Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.

Isgrig K, Shteamer JW, Belyantseva IA, Drummond MC, Fitzgerald TS, Vijayakumar S, Jones SM, Griffith AJ, Friedman TB, Cunningham LL, Chien WW. Isgrig K, et al. Among authors: chien ww. Mol Ther. 2017 Mar 1;25(3):780-791. doi: 10.1016/j.ymthe.2017.01.007. Epub 2017 Feb 21. Mol Ther. 2017. PMID: 28254438 Free PMC article.

6

Posterior Semicircular Canal Approach for Inner Ear Gene Delivery in Neonatal Mouse.

Isgrig K, Chien WW. Isgrig K, et al. Among authors: chien ww. J Vis Exp. 2018 Mar 2;(133):56648. doi: 10.3791/56648. J Vis Exp. 2018. PMID: 29553564 Free PMC article.

7

SLC26A4-linked CEVA haplotype correlates with phenotype in patients with enlargement of the vestibular aqueduct.

Chao JR, Chattaraj P, Munjal T, Honda K, King KA, Zalewski CK, Chien WW, Brewer CC, Griffith AJ. Chao JR, et al. Among authors: chien ww. BMC Med Genet. 2019 Jul 2;20(1):118. doi: 10.1186/s12881-019-0853-4. BMC Med Genet. 2019. PMID: 31266487 Free PMC article.

8

Combined AAV-mediated gene replacement therapy improves auditory function in a mouse model of human DFNB42 deafness.

Isgrig K, Cartagena-Rivera AX, Wang HJ, Grati M, Fernandez KA, Friedman TB, Belyantseva IA, Chien W. Isgrig K, et al. Mol Ther. 2023 Sep 6;31(9):2783-2795. doi: 10.1016/j.ymthe.2023.07.014. Epub 2023 Jul 22. Mol Ther. 2023. PMID: 37481704 Free PMC article.

9

Interaction between the TBC1D24 TLDc domain and the KIBRA C2 domain is disrupted by two epilepsy-associated TBC1D24 missense variants.

Tona R, Inagaki S, Ishibashi Y, Faridi R, Yousaf R, Roux I, Wilson E, Fenollar-Ferrer C, Chien WW, Belyantseva IA, Friedman TB. Tona R, et al. Among authors: chien ww. J Biol Chem. 2024 Sep;300(9):107725. doi: 10.1016/j.jbc.2024.107725. Epub 2024 Aug 28. J Biol Chem. 2024. PMID: 39214300 Free PMC article.

10

Hearing loss associated with enlarged vestibular aqueduct and zero or one mutant allele of SLC26A4.

Rose J, Muskett JA, King KA, Zalewski CK, Chattaraj P, Butman JA, Kenna MA, Chien WW, Brewer CC, Griffith AJ. Rose J, et al. Among authors: chien ww. Laryngoscope. 2017 Jul;127(7):E238-E243. doi: 10.1002/lary.26418. Epub 2016 Nov 15. Laryngoscope. 2017. PMID: 27859305 Free PMC article.

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