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ASPYRE-Lung: validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in FFPE tissue.
Evans RT, Gillon-Zhang E, Brown JN, Knudsen KE, King C, Green AS, Silva AL, Mordaka JM, Palmer RN, Tomassini A, Collazos A, Xyrafaki C, Turner I, Ho CH, Nugent D, Jose J, Andreazza S, Potts ND, von Bargen K, Gray ER, Stolarek-Januszkiewicz M, Cooke A, Reddi HV, Balmforth BW, Osborne RJ. Evans RT, et al. Front Oncol. 2024 Sep 25;14:1420162. doi: 10.3389/fonc.2024.1420162. eCollection 2024. Front Oncol. 2024. PMID: 39386190 Free PMC article.
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke.
Evans R, Bolduc PN, Pfaffenbach M, Gao F, May-Dracka T, Fang T, Hopkins BT, Chodaparambil JV, Henry KL, Li P, Metrick C, Nelson A, Trapa P, Thomas A, Burkly L, Peterson EA. Evans R, et al. J Med Chem. 2024 Mar 28;67(6):4676-4690. doi: 10.1021/acs.jmedchem.3c02226. Epub 2024 Mar 11. J Med Chem. 2024. PMID: 38467640
Evaluation of the ASPYRE-Lung targeted variant panel: a rapid, low-input solution for non-small cell lung cancer biomarker testing and experience from three independent sites.
Herlihy SE, Gentile C, Scott SJ, Smith BA, Stoll KA, Schilter KF, Mordaka JM, Palmer RN, Xyrafaki C, Gillon-Zhang E, King C, Evans RT, Green AS, Silva AL, Stolarek-Januszkiewicz M, von Bargen K, Turner I, Ho CH, Collazos A, Potts ND, Nugent D, Jose J, Gray ER, Shapiro E, Levin WJ, Cooke A, Balmforth BW, Osborne RJ, Reddi HV, Van Deerlin VM. Herlihy SE, et al. Among authors: evans rt. Transl Lung Cancer Res. 2024 Nov 30;13(11):3083-3095. doi: 10.21037/tlcr-24-525. Epub 2024 Nov 28. Transl Lung Cancer Res. 2024. PMID: 39670005 Free PMC article.
154 results