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Impact of genomic background and developmental state on signaling pathways and response to therapy in glioblastoma patient-derived cells.
Berezovsky A, Nuga O, Datta I, Bergman K, Sabedot T, Gurdziel K, Irtenkauf S, Hasselbach L, Meng Y, Mueller C, Petricoin EF, Brown S, Purandare N, Aras S, Mikkelsen T, Poisson L, Noushmehr H, Ruden D, deCarvalho AC. Berezovsky A, et al. Among authors: noushmehr h. bioRxiv [Preprint]. 2024 Sep 23:2024.03.14.585115. doi: 10.1101/2024.03.14.585115. bioRxiv. 2024. PMID: 39386580 Free PMC article. Preprint.
A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence.
de Souza CF, Sabedot TS, Malta TM, Stetson L, Morozova O, Sokolov A, Laird PW, Wiznerowicz M, Iavarone A, Snyder J, deCarvalho A, Sanborn Z, McDonald KL, Friedman WA, Tirapelli D, Poisson L, Mikkelsen T, Carlotti CG Jr, Kalkanis S, Zenklusen J, Salama SR, Barnholtz-Sloan JS, Noushmehr H. de Souza CF, et al. Among authors: noushmehr h. Cell Rep. 2018 Apr 10;23(2):637-651. doi: 10.1016/j.celrep.2018.03.107. Cell Rep. 2018. PMID: 29642018 Free PMC article.
A serum-based DNA methylation assay provides accurate detection of glioma.
Sabedot TS, Malta TM, Snyder J, Nelson K, Wells M, deCarvalho AC, Mukherjee A, Chitale DA, Mosella MS, Sokolov A, Asmaro KP, Robin A, Rosenblum ML, Mikkelsen T, Rock J, Poisson LM, Lee I, Walbert T, Kalkanis S, Iavarone A, Castro AV, Noushmehr H. Sabedot TS, et al. Among authors: noushmehr h. Neuro Oncol. 2021 Sep 1;23(9):1494-1508. doi: 10.1093/neuonc/noab023. Neuro Oncol. 2021. PMID: 33560371 Free PMC article.
Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas.
Herrgott GA, Snyder JM, She R, Malta TM, Sabedot TS, Lee IY, Pawloski J, Podolsky-Gondim GG, Asmaro KP, Zhang J, Cannella CE, Nelson K, Thomas B, deCarvalho AC, Hasselbach LA, Tundo KM, Newaz R, Transou A, Morosini N, Francisco V, Poisson LM, Chitale D, Mukherjee A, Mosella MS, Robin AM, Walbert T, Rosenblum M, Mikkelsen T, Kalkanis S, Tirapelli DPC, Weisenberger DJ, Carlotti CG Jr, Rock J, Castro AV, Noushmehr H. Herrgott GA, et al. Among authors: noushmehr h. Nat Commun. 2023 Sep 13;14(1):5669. doi: 10.1038/s41467-023-41434-z. Nat Commun. 2023. PMID: 37704607 Free PMC article.
DNA methylation-based signatures classify sporadic pituitary tumors according to clinicopathological features.
Mosella MS, Sabedot TS, Silva TC, Malta TM, Dezem FS, Asmaro KP, Wells M, Mukherjee A, Poisson LM, Snyder J, deCarvalho AC, Walbert T, Aho T, Kalkanis S, Elias PC, Antonini SR, Rock J, Noushmehr H, Castro M, Castro AV. Mosella MS, et al. Among authors: noushmehr h. Neuro Oncol. 2021 Aug 2;23(8):1292-1303. doi: 10.1093/neuonc/noab044. Neuro Oncol. 2021. PMID: 33631002 Free PMC article.
Detection of tumor-specific DNA methylation markers in the blood of patients with pituitary neuroendocrine tumors.
Herrgott GA, Asmaro KP, Wells M, Sabedot TS, Malta TM, Mosella MS, Nelson K, Scarpace L, Barnholtz-Sloan JS, Sloan AE, Selman WR, deCarvalho AC, Poisson LM, Mukherjee A, Robin AM, Lee IY, Snyder J, Walbert T, Rosenblum M, Mikkelsen T, Bhan A, Craig J, Kalkanis S, Rock J, Noushmehr H, Castro AV. Herrgott GA, et al. Among authors: noushmehr h. Neuro Oncol. 2022 Jul 1;24(7):1126-1139. doi: 10.1093/neuonc/noac050. Neuro Oncol. 2022. PMID: 35212383 Free PMC article.
The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen.
Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM; Consortium The GLASS; Verhaak RGW, Iavarone A, Noushmehr H. Malta TM, et al. Among authors: noushmehr h. Cancer Res. 2024 Mar 4;84(5):741-756. doi: 10.1158/0008-5472.CAN-23-2093. Cancer Res. 2024. PMID: 38117484 Free PMC article.
The somatic genomic landscape of glioblastoma.
Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, Barnholtz-Sloan J, Zou L, Vegesna R, Shukla SA, Ciriello G, Yung WK, Zhang W, Sougnez C, Mikkelsen T, Aldape K, Bigner DD, Van Meir EG, Prados M, Sloan A, Black KL, Eschbacher J, Finocchiaro G, Friedman W, Andrews DW, Guha A, Iacocca M, O'Neill BP, Foltz G, Myers J, Weisenberger DJ, Penny R, Kucherlapati R, Perou CM, Hayes DN, Gibbs R, Marra M, Mills GB, Lander E, Spellman P, Wilson R, Sander C, Weinstein J, Meyerson M, Gabriel S, Laird PW, Haussler D, Getz G, Chin L; TCGA Research Network. Brennan CW, et al. Among authors: noushmehr h. Cell. 2013 Oct 10;155(2):462-77. doi: 10.1016/j.cell.2013.09.034. Cell. 2013. PMID: 24120142 Free PMC article.
128 results