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A pathogenic mutation in the ALS/FTD gene VCP induces mitochondrial hypermetabolism by modulating the permeability transition pore.
Vanderhaeghe S, Prerad J, Tharkeshwar AK, Goethals E, Vints K, Beckers J, Scheveneels W, Debroux E, Princen K, Van Damme P, Fivaz M, Griffioen G, Van Den Bosch L. Vanderhaeghe S, et al. Among authors: fivaz m. Acta Neuropathol Commun. 2024 Oct 10;12(1):161. doi: 10.1186/s40478-024-01866-0. Acta Neuropathol Commun. 2024. PMID: 39390590 Free PMC article.
Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
Princen K, Van Dooren T, van Gorsel M, Louros N, Yang X, Dumbacher M, Bastiaens I, Coupet K, Dupont S, Cuveliers E, Lauwers A, Laghmouchi M, Vanwelden T, Carmans S, Van Damme N, Duhamel H, Vansteenkiste S, Prerad J, Pipeleers K, Rodiers O, De Ridder L, Claes S, Busschots Y, Pringels L, Verhelst V, Debroux E, Brouwer M, Lievens S, Tavernier J, Farinelli M, Hughes-Asceri S, Voets M, Winderickx J, Wera S, de Wit J, Schymkowitz J, Rousseau F, Zetterberg H, Cummings JL, Annaert W, Cornelissen T, De Winter H, De Witte K, Fivaz M, Griffioen G. Princen K, et al. Among authors: fivaz m. Science. 2024 May 31;384(6699):eadd6260. doi: 10.1126/science.add6260. Epub 2024 May 31. Science. 2024. PMID: 38815015
Editorial: Imaging Synapse Structure and Function.
Augustine GJ, Fivaz M. Augustine GJ, et al. Among authors: fivaz m. Front Synaptic Neurosci. 2016 Dec 15;8:36. doi: 10.3389/fnsyn.2016.00036. eCollection 2016. Front Synaptic Neurosci. 2016. PMID: 28018205 Free PMC article. No abstract available.
49 results