Wang E - Search Results

1

Alternative splicing dysregulation across tissue and therapeutic approaches in a mouse model of myotonic dystrophy type 1.

Hicks SM, Frias JA, Mishra SK, Scotti M, Muscato DR, Valero MC, Adams LM, Cleary JD, Nakamori M, Wang E, Berglund JA. Hicks SM, et al. Among authors: wang e. Mol Ther Nucleic Acids. 2024 Sep 13;35(4):102338. doi: 10.1016/j.omtn.2024.102338. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39391766 Free PMC article.

2

Conservation of context-dependent splicing activity in distant Muscleblind homologs.

Oddo JC, Saxena T, McConnell OL, Berglund JA, Wang ET. Oddo JC, et al. Nucleic Acids Res. 2016 Sep 30;44(17):8352-62. doi: 10.1093/nar/gkw735. Epub 2016 Aug 23. Nucleic Acids Res. 2016. PMID: 27557707 Free PMC article.

3

Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy.

Thomas JD, Sznajder ŁJ, Bardhi O, Aslam FN, Anastasiadis ZP, Scotti MM, Nishino I, Nakamori M, Wang ET, Swanson MS. Thomas JD, et al. Genes Dev. 2017 Jun 1;31(11):1122-1133. doi: 10.1101/gad.300590.117. Epub 2017 Jul 11. Genes Dev. 2017. PMID: 28698297 Free PMC article.

4

An engineered RNA binding protein with improved splicing regulation.

Hale MA, Richardson JI, Day RC, McConnell OL, Arboleda J, Wang ET, Berglund JA. Hale MA, et al. Nucleic Acids Res. 2018 Apr 6;46(6):3152-3168. doi: 10.1093/nar/gkx1304. Nucleic Acids Res. 2018. PMID: 29309648 Free PMC article.

5

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.

Reddy K, Jenquin JR, McConnell OL, Cleary JD, Richardson JI, Pinto BS, Haerle MC, Delgado E, Planco L, Nakamori M, Wang ET, Berglund JA. Reddy K, et al. Among authors: wang et. Proc Natl Acad Sci U S A. 2019 Oct 15;116(42):20991-21000. doi: 10.1073/pnas.1901893116. Epub 2019 Sep 30. Proc Natl Acad Sci U S A. 2019. PMID: 31570586 Free PMC article.

6

Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening.

Jenquin JR, O'Brien AP, Poukalov K, Lu Y, Frias JA, Shorrock HK, Richardson JI, Mazdiyasni H, Yang H, Huigens RW 3rd, Boykin D, Ranum LPW, Cleary JD, Wang ET, Berglund JA. Jenquin JR, et al. iScience. 2022 Apr 4;25(5):104198. doi: 10.1016/j.isci.2022.104198. eCollection 2022 May 20. iScience. 2022. PMID: 35479399 Free PMC article.

7

Alternative Splicing Outcomes Across an RNA-Binding Protein Concentration Gradient.

Ellis JA, Hale MA, Cleary JD, Wang ET, Andrew Berglund J. Ellis JA, et al. J Mol Biol. 2023 Aug 1;435(15):168156. doi: 10.1016/j.jmb.2023.168156. Epub 2023 May 23. J Mol Biol. 2023. PMID: 37230319 Free article.

8

Myospreader improves gene editing in skeletal muscle by myonuclear propagation.

Poukalov KK, Valero MC, Muscato DR, Adams LM, Chun H, Lee YI, Andrade NS, Zeier Z, Sweeney HL, Wang ET. Poukalov KK, et al. bioRxiv [Preprint]. 2023 Nov 6:2023.11.06.565807. doi: 10.1101/2023.11.06.565807. bioRxiv. 2023. Update in: Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2321438121. doi: 10.1073/pnas.2321438121. PMID: 37986992 Free PMC article. Updated. Preprint.

9

Myospreader improves gene editing in skeletal muscle by myonuclear propagation.

Poukalov KK, Valero MC, Muscato DR, Adams LM, Chun H, Lee YI, Andrade NS, Zeier Z, Sweeney HL, Wang ET. Poukalov KK, et al. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2321438121. doi: 10.1073/pnas.2321438121. Epub 2024 Apr 30. Proc Natl Acad Sci U S A. 2024. PMID: 38687782 Free PMC article.

10

Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy.

Wagner SD, Struck AJ, Gupta R, Farnsworth DR, Mahady AE, Eichinger K, Thornton CA, Wang ET, Berglund JA. Wagner SD, et al. Among authors: wang et. PLoS Genet. 2016 Sep 28;12(9):e1006316. doi: 10.1371/journal.pgen.1006316. eCollection 2016 Sep. PLoS Genet. 2016. PMID: 27681373 Free PMC article.

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