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BRCA promoter methylation in triple-negative breast cancer is preserved in xenograft models and represents a potential therapeutic marker for PARP inhibitors.
Däster K, Hench J, Diepenbruck M, Volkmann K, Rouchon A, Palafox M, Miragaya JG, Preca BT, Kurzeder C, Weber WP, Bentires-Alj M, Soysal SD, Muenst S. Däster K, et al. Among authors: bentires alj m. Breast Cancer Res Treat. 2024 Oct 11. doi: 10.1007/s10549-024-07502-8. Online ahead of print. Breast Cancer Res Treat. 2024. PMID: 39392573
Single-cell Analysis Reveals Inter- and Intratumour Heterogeneity in Metastatic Breast Cancer.
Hamelin B, Obradović MMS, Sethi A, Kloc M, Münst S, Beisel C, Eschbach K, Kohler H, Soysal S, Vetter M, Weber WP, Stadler MB, Bentires-Alj M. Hamelin B, et al. Among authors: bentires alj m. J Mammary Gland Biol Neoplasia. 2023 Dec 8;28(1):26. doi: 10.1007/s10911-023-09551-z. J Mammary Gland Biol Neoplasia. 2023. PMID: 38066300 Free PMC article.
Imagine beyond: recent breakthroughs and next challenges in mammary gland biology and breast cancer research.
van Amerongen R, Bentires-Alj M, van Boxtel AL, Clarke RB, Fre S, Suarez EG, Iggo R, Jechlinger M, Jonkers J, Mikkola ML, Koledova ZS, Sørlie T, Vivanco MD. van Amerongen R, et al. Among authors: bentires alj m. J Mammary Gland Biol Neoplasia. 2023 Jul 14;28(1):17. doi: 10.1007/s10911-023-09544-y. J Mammary Gland Biol Neoplasia. 2023. PMID: 37450065 Free PMC article. Review.
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer.
Amante RJ, Jehanno C, De Silva D, Coissieux MM, Ackerknecht M, Romanet V, Sethi A, Hamelin B, Preca BT, Piscuoglio S, Ng CKY, Mohseni M, Bentires-Alj M. Amante RJ, et al. Among authors: bentires alj m. J Mammary Gland Biol Neoplasia. 2023 Jun 9;28(1):13. doi: 10.1007/s10911-023-09539-9. J Mammary Gland Biol Neoplasia. 2023. PMID: 37294349 Free PMC article.
Nicotinamide N-methyltransferase sustains a core epigenetic program that promotes metastatic colonization in breast cancer.
Couto JP, Vulin M, Jehanno C, Coissieux MM, Hamelin B, Schmidt A, Ivanek R, Sethi A, Bräutigam K, Frei AL, Hager C, Manivannan M, Gómez-Miragaya J, Obradović MM, Varga Z, Koelzer VH, Mertz KD, Bentires-Alj M. Couto JP, et al. Among authors: bentires alj m. EMBO J. 2023 Jul 3;42(13):e112559. doi: 10.15252/embj.2022112559. Epub 2023 Jun 1. EMBO J. 2023. PMID: 37259596 Free PMC article.
N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer.
Auf der Maur P, Trefny MP, Baumann Z, Vulin M, Correia AL, Diepenbruck M, Kramer N, Volkmann K, Preca BT, Ramos P, Leroy C, Eichlisberger T, Buczak K, Zilli F, Okamoto R, Rad R, Jensen MR, Fritsch C, Zippelius A, Stadler MB, Bentires-Alj M. Auf der Maur P, et al. Among authors: bentires alj m. Cell Rep Med. 2023 Apr 18;4(4):101002. doi: 10.1016/j.xcrm.2023.101002. Epub 2023 Apr 11. Cell Rep Med. 2023. PMID: 37044095 Free PMC article.
Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy.
Trefny MP, Kirchhammer N, Auf der Maur P, Natoli M, Schmid D, Germann M, Fernandez Rodriguez L, Herzig P, Lötscher J, Akrami M, Stinchcombe JC, Stanczak MA, Zingg A, Buchi M, Roux J, Marone R, Don L, Lardinois D, Wiese M, Jeker LT, Bentires-Alj M, Rossy J, Thommen DS, Griffiths GM, Läubli H, Hess C, Zippelius A. Trefny MP, et al. Among authors: bentires alj m. Nat Commun. 2023 Feb 2;14(1):86. doi: 10.1038/s41467-022-35583-w. Nat Commun. 2023. PMID: 36732507 Free PMC article.
Live slow-frozen human tumor tissues viable for 2D, 3D, ex vivo cultures and single-cell RNAseq.
Restivo G, Tastanova A, Balázs Z, Panebianco F, Diepenbruck M, Ercan C, Preca BT, Hafner J, Weber WP, Kurzeder C, Vetter M, Soysal SM, Beisel C, Bentires-Alj M, Piscuoglio S, Krauthammer M, Levesque MP. Restivo G, et al. Among authors: bentires alj m. Commun Biol. 2022 Oct 28;5(1):1144. doi: 10.1038/s42003-022-04025-0. Commun Biol. 2022. PMID: 36307545 Free PMC article.
106 results