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Page 1
Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling.
Rathore M, Curry K, Huang W, Wright M, Martin D, Baek J, Taylor D, Miyagi M, Tang W, Feng H, Li Y, Wang Z, Graor H, Willis J, Bryson E, Boutros CS, Desai O, Islam BN, Ellis LM, Moss SE, Winter JM, Greenwood J, Wang R. Rathore M, et al. Among authors: graor h. Gastroenterology. 2024 Oct 10:S0016-5085(24)05566-5. doi: 10.1053/j.gastro.2024.10.004. Online ahead of print. Gastroenterology. 2024. PMID: 39393543 Free article.
Wild-type IDH1 inhibition enhances chemotherapy response in melanoma.
Zarei M, Hajihassani O, Hue JJ, Graor HJ, Loftus AW, Rathore M, Vaziri-Gohar A, Asara JM, Winter JM, Rothermel LD. Zarei M, et al. Among authors: graor hj. J Exp Clin Cancer Res. 2022 Sep 24;41(1):283. doi: 10.1186/s13046-022-02489-w. J Exp Clin Cancer Res. 2022. PMID: 36153582 Free PMC article.
Increased glucose availability sensitizes pancreatic cancer to chemotherapy.
Vaziri-Gohar A, Hue JJ, Abbas A, Graor HJ, Hajihassani O, Zarei M, Titomihelakis G, Feczko J, Rathore M, Chelstowska S, Loftus AW, Wang R, Zarei M, Goudarzi M, Zhang R, Willard B, Zhang L, Kresak A, Willis JE, Wang GM, Tatsuoka C, Salvino JM, Bederman I, Brunengraber H, Lyssiotis CA, Brody JR, Winter JM. Vaziri-Gohar A, et al. Among authors: graor hj. Nat Commun. 2023 Jun 28;14(1):3823. doi: 10.1038/s41467-023-38921-8. Nat Commun. 2023. PMID: 37380658 Free PMC article.
IDH1 Inhibition Potentiates Chemotherapy Efficacy in Pancreatic Cancer.
Zarei M, Hajihassani O, Hue JJ, Loftus AW, Graor HJ, Nakazzi F, Naji P, Boutros CS, Uppin V, Vaziri-Gohar A, Shalaby AS, Asara JM, Rothermel LD, Brody JR, Winter JM. Zarei M, et al. Among authors: graor hj. Cancer Res. 2024 Sep 16;84(18):3072-3085. doi: 10.1158/0008-5472.CAN-23-1895. Cancer Res. 2024. PMID: 38843355 Free PMC article.
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
Hue JJ, Graor HJ, Zarei M, Katayama ES, Ji K, Hajihassani O, Loftus AW, Vaziri-Gohar A, Winter JM. Hue JJ, et al. Among authors: graor hj. Mol Cancer Ther. 2022 Dec 2;21(12):1810-1822. doi: 10.1158/1535-7163.MCT-22-0055. Mol Cancer Ther. 2022. PMID: 36190971
Clinical development of IDH1 inhibitors for cancer therapy.
Zarei M, Hue JJ, Hajihassani O, Graor HJ, Katayama ES, Loftus AW, Bajor D, Rothermel LD, Vaziri-Gohar A, Winter JM. Zarei M, et al. Cancer Treat Rev. 2022 Feb;103:102334. doi: 10.1016/j.ctrv.2021.102334. Epub 2021 Dec 28. Cancer Treat Rev. 2022. PMID: 34974243 Review.
Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.
Vaziri-Gohar A, Cassel J, Mohammed FS, Zarei M, Hue JJ, Hajihassani O, Graor HJ, Srikanth YVV, Karim SA, Abbas A, Prendergast E, Chen V, Katayama ES, Dukleska K, Khokhar I, Andren A, Zhang L, Wu C, Erokwu B, Flask CA, Zarei M, Wang R, Rothermel LD, Romani AMP, Bowers J, Getts R, Tatsuoka C, Morton JP, Bederman I, Brunengraber H, Lyssiotis CA, Salvino JM, Brody JR, Winter JM. Vaziri-Gohar A, et al. Among authors: graor hj. Nat Cancer. 2022 Jul;3(7):852-865. doi: 10.1038/s43018-022-00393-y. Epub 2022 Jun 9. Nat Cancer. 2022. PMID: 35681100 Free PMC article.
18 results