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Aplospojaveedins A-C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategy.
Gao Y, Frank M, Teusch N, Woschko D, Janiak C, Mándi A, Kurtán T, Hartmann R, Schiedlauske K, van Geelen L, Kalscheuer R, Kaiser J, Gertzen CGW, Gohlke H, Wang BG, Proksch P, Liu Z. Gao Y, et al. Among authors: gohlke h. Front Microbiol. 2024 Sep 27;15:1458622. doi: 10.3389/fmicb.2024.1458622. eCollection 2024. Front Microbiol. 2024. PMID: 39397793 Free PMC article.
Regulation of STING activity in DNA sensing by ISG15 modification.
Lin C, Kuffour EO, Fuchs NV, Gertzen CGW, Kaiser J, Hirschenberger M, Tang X, Xu HC, Michel O, Tao R, Haase A, Martin U, Kurz T, Drexler I, Görg B, Lang PA, Luedde T, Sparrer KMJ, Gohlke H, König R, Münk C. Lin C, et al. Among authors: gohlke h. Cell Rep. 2023 Nov 28;42(11):113277. doi: 10.1016/j.celrep.2023.113277. Epub 2023 Oct 20. Cell Rep. 2023. PMID: 37864791 Free article.
Synthesis and biological evaluation of novel MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after intoxication with nerve agents.
Bernauer T, Nitsche V, Kaiser J, Gertzen CGW, Höfner G, Niessen KV, Seeger T, Steinritz D, Worek F, Gohlke H, Wanner KT, Paintner FF. Bernauer T, et al. Among authors: gohlke h. Toxicol Lett. 2024 Jun;397:151-162. doi: 10.1016/j.toxlet.2024.05.011. Epub 2024 May 15. Toxicol Lett. 2024. PMID: 38759939 Free article.
Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations.
Pacholewska A, Lienhard M, Brüggemann M, Hänel H, Bilalli L, Königs A, Heß F, Becker K, Köhrer K, Kaiser J, Gohlke H, Gattermann N, Hallek M, Herling CD, König J, Grimm C, Herwig R, Zarnack K, Schweiger MR. Pacholewska A, et al. Among authors: gohlke h. Genome Res. 2024 Nov 20;34(11):1832-1848. doi: 10.1101/gr.279327.124. Genome Res. 2024. PMID: 39271291 Free PMC article.
Novel meriolin derivatives potently inhibit cell cycle progression and transcription in leukemia and lymphoma cells via inhibition of cyclin-dependent kinases (CDKs).
Schmitt L, Hoppe J, Cea-Medina P, Bruch PM, Krings KS, Lechtenberg I, Drießen D, Peter C, Bhatia S, Dietrich S, Stork B, Fritz G, Gohlke H, Müller TJJ, Wesselborg S. Schmitt L, et al. Among authors: gohlke h. Cell Death Discov. 2024 Jun 11;10(1):279. doi: 10.1038/s41420-024-02056-6. Cell Death Discov. 2024. PMID: 38862521 Free PMC article.
CD63 as novel target for nanoemulsion-based 19F MRI imaging and drug delivery to activated cardiac fibroblasts.
Euan Martínez AA, Bergmann AK, Tellkamp F, Schott-Verdugo S, Bouvain P, Steinhausen J, Bahr J, Kmietczyk V, Bencun M, Flögel U, Distler JHW, Krueger M, Völkers M, Czekelius C, Gohlke H, Temme S, Hesse J, Schrader J. Euan Martínez AA, et al. Among authors: gohlke h. Theranostics. 2025 Jan 1;15(1):1-18. doi: 10.7150/thno.96990. eCollection 2025. Theranostics. 2025. PMID: 39744226 Free PMC article.
406 results