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Page 1
Lipid Trajectories Improve Risk Models for Alzheimer's Disease and Mild Cognitive Impairment.
Chase BA, Frigerio R, Yucus CJ, Patel S, Maraganore D, Sanders AR, Duan J, Markopoulou K. Chase BA, et al. Among authors: sanders ar. medRxiv [Preprint]. 2024 Sep 28:2024.09.27.24314494. doi: 10.1101/2024.09.27.24314494. medRxiv. 2024. Update in: J Lipid Res. 2024 Nov 23;66(1):100714. doi: 10.1016/j.jlr.2024.100714 PMID: 39399044 Free PMC article. Updated. Preprint.
Alzheimer's disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication.
Zhao X, Li Y, Zhang S, Sudwarts A, Zhang H, Kozlova A, Moulton MJ, Goodman LD, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J. Zhao X, et al. Among authors: sanders ar. medRxiv [Preprint]. 2024 Aug 15:2024.08.14.24312009. doi: 10.1101/2024.08.14.24312009. medRxiv. 2024. PMID: 39185522 Free PMC article. Preprint.
Expanding the genetic landscape of endometriosis: Integrative -omics analyses uncover key pathways from a multi-ancestry study of over 900,000 women.
Guare LA, Das J, Caruth L, Rajagopalan A, Akerele AT, Brumpton BM, Chen TT, Kottyan L, Lin YF, Moreno E, Mulford AJ, Rovite V, Sanders AR, Dombrovska MS, Elhadad N, Hill A, Jarvik G, Jaworski J, Luo Y, Namba S, Okada Y, Shi Y, Shirai Y, Shortt J, Wei WQ, Weng C, Yamamoto Y, Chapman S, Zhou W, Velez Edwards DR, Setia-Verma S. Guare LA, et al. Among authors: sanders ar. medRxiv [Preprint]. 2024 Nov 29:2024.11.26.24316723. doi: 10.1101/2024.11.26.24316723. medRxiv. 2024. PMID: 39649588 Free PMC article. Preprint.
An Integrative Migraine Polygenic Risk Score Is Associated with Age at Onset But Not Chronification.
Chase BA, Frigerio R, Rubin S, Franada T, Semenov I, Meyers S, Bergman-Bock S, Mark A, Freedom T, Marcus R, Dafer R, Wei J, Zheng SL, Xu J, Mulford AJ, Sanders AR, Pham A, Epshteyn A, Maraganore D, Markopoulou K. Chase BA, et al. Among authors: sanders ar. J Clin Med. 2024 Oct 29;13(21):6483. doi: 10.3390/jcm13216483. J Clin Med. 2024. PMID: 39518622 Free PMC article.
Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs.
Zhang H, McCarroll A, Peyton L, Díaz de León-Guerrerro S, Zhang S, Gowda P, Sirkin D, ElAchwah M, Duhe A, Wood WG, Jamison B, Tracy G, Pollak R, Hart RP, Pato CN, Mulle JG, Sanders AR, Pang ZP, Duan J. Zhang H, et al. Among authors: sanders ar. Stem Cell Reports. 2024 Oct 8;19(10):1489-1504. doi: 10.1016/j.stemcr.2024.08.003. Epub 2024 Sep 12. Stem Cell Reports. 2024. PMID: 39270650 Free PMC article.
Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Trastulla L, Dolgalev G, Moser S, Jiménez-Barrón LT, Andlauer TFM, von Scheidt M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Budde M, Heilbronner U, Papiol S, Teumer A, Homuth G, Völzke H, Dörr M, Falkai P, Schulze TG, Gagneur J, Iorio F, Müller-Myhsok B, Schunkert H, Ziller MJ. Trastulla L, et al. Nat Commun. 2024 Jul 1;15(1):5534. doi: 10.1038/s41467-024-49338-2. Nat Commun. 2024. PMID: 38951512 Free PMC article.
186 results