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Page 1
Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors.
van Belzen IAEM, van Tuil M, Badloe S, Janse A, Verwiel ETP, Santoso M, de Vos S, Baker-Hernandez J, Kerstens HHD, Solleveld-Westerink N, Meister MT, Drost J, van den Heuvel-Eibrink MM, Merks JHM, Molenaar JJ, Peng WC, Tops BBJ, Holstege FCP, Kemmeren P, Hehir-Kwa JY. van Belzen IAEM, et al. Among authors: molenaar jj. Cell Genom. 2024 Nov 13;4(11):100675. doi: 10.1016/j.xgen.2024.100675. Epub 2024 Oct 14. Cell Genom. 2024. PMID: 39406233 Free article.
A multispectral 3D live organoid imaging platform to screen probes for fluorescence guided surgery.
Jeremiasse B, van Ineveld RL, Bok V, Kleinnijenhuis M, de Blank S, Alieva M, Johnson HR, van Vliet EJ, Zeeman AL, Wellens LM, Llibre-Palomar G, Barrera Román M, Di Maggio A, Dekkers JF, Oliveira S, Vahrmeijer AL, Molenaar JJ, Wijnen MH, van der Steeg AF, Wehrens EJ, Rios AC. Jeremiasse B, et al. Among authors: molenaar jj. EMBO Mol Med. 2024 Jul;16(7):1495-1514. doi: 10.1038/s44321-024-00084-4. Epub 2024 Jun 3. EMBO Mol Med. 2024. PMID: 38831131 Free PMC article.
Neuroblastoma plasticity during metastatic progression stems from the dynamics of an early sympathetic transcriptomic trajectory.
Villalard B, Boltjes A, Reynaud F, Imbaud O, Thoinet K, Timmerman I, Croze S, Theoulle E, Atzeni G, Lachuer J, Molenaar JJ, Tytgat GAM, Delloye-Bourgeois C, Castellani V. Villalard B, et al. Among authors: molenaar jj. Nat Commun. 2024 Nov 6;15(1):9570. doi: 10.1038/s41467-024-53776-3. Nat Commun. 2024. PMID: 39500881 Free PMC article.
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.
Wienke J, Visser LL, Kholosy WM, Keller KM, Barisa M, Poon E, Munnings-Tomes S, Himsworth C, Calton E, Rodriguez A, Bernardi R, van den Ham F, van Hooff SR, Matser YAH, Tas ML, Langenberg KPS, Lijnzaad P, Borst AL, Zappa E, Bergsma FJ, Strijker JGM, Verhoeven BM, Mei S, Kramdi A, Restuadi R, Sanchez-Bernabeu A, Cornel AM, Holstege FCP, Gray JC, Tytgat GAM, Scheijde-Vermeulen MA, Wijnen MHWA, Dierselhuis MP, Straathof K, Behjati S, Wu W, Heck AJR, Koster J, Nierkens S, Janoueix-Lerosey I, de Krijger RR, Baryawno N, Chesler L, Anderson J, Caron HN, Margaritis T, van Noesel MM, Molenaar JJ. Wienke J, et al. Among authors: molenaar jj. Cancer Cell. 2024 Feb 12;42(2):283-300.e8. doi: 10.1016/j.ccell.2023.12.008. Epub 2024 Jan 4. Cancer Cell. 2024. PMID: 38181797 Free PMC article.
Two opposing gene expression patterns within ATRX aberrant neuroblastoma.
van Gerven MR, Schild L, van Arkel J, Koopmans B, Broeils LA, Meijs LAM, van Oosterhout R, van Noesel MM, Koster J, van Hooff SR, Molenaar JJ, van den Boogaard ML. van Gerven MR, et al. Among authors: molenaar jj. PLoS One. 2023 Aug 4;18(8):e0289084. doi: 10.1371/journal.pone.0289084. eCollection 2023. PLoS One. 2023. PMID: 37540673 Free PMC article.
Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS.
van Belzen IAEM, Cai C, van Tuil M, Badloe S, Strengman E, Janse A, Verwiel ETP, van der Leest DFM, Kester L, Molenaar JJ, Meijerink J, Drost J, Peng WC, Kerstens HHD, Tops BBJ, Holstege FCP, Kemmeren P, Hehir-Kwa JY. van Belzen IAEM, et al. Among authors: molenaar jj. BMC Cancer. 2023 Jul 3;23(1):618. doi: 10.1186/s12885-023-11054-3. BMC Cancer. 2023. PMID: 37400763 Free PMC article.
Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.
Heipertz AE, Pajtler KW, Pfaff E, Schramm K, Blattner-Johnson M, Milde T, Jones BC, Zuliani C, Hutter C, Lohi O, Kattamis A, Dachowska-Kalwak I, Nilsson A, Gerber NU, Langenberg KPS, Goemans B, Zwaan CM, Molenaar JJ, Jäger N, Dirksen U, Witt R, Pfister SM, Jones DTW, Kopp-Schneider A, Witt O, van Tilburg CM. Heipertz AE, et al. Among authors: molenaar jj. JCO Precis Oncol. 2023 Jun;7:e2300015. doi: 10.1200/PO.23.00015. JCO Precis Oncol. 2023. PMID: 37364231
99 results