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A CXCR4 partial agonist improves immunotherapy by targeting polymorphonuclear myeloid-derived suppressor cells and cancer-driven granulopoiesis.
Qian J, Ma C, Waterbury QT, Zhi X, Moon CS, Tu R, Kobayashi H, Wu F, Zheng B, Zeng Y, Zheng H, Ochiai Y, White RA, Harle DW, LaBella JS, Zamechek LB, Hu LZ, Moy RH, Han AS, Daugherty B, Lederman S, Wang TC. Qian J, et al. Among authors: white ra. bioRxiv [Preprint]. 2024 Oct 11:2024.10.09.617228. doi: 10.1101/2024.10.09.617228. bioRxiv. 2024. PMID: 39416177 Free PMC article. Preprint.
Acute Intestinal Inflammation Depletes/Recruits Histamine-Expressing Myeloid Cells From the Bone Marrow Leading to Exhaustion of MB-HSCs.
Fu N, Wu F, Jiang Z, Kim W, Ruan T, Malagola E, Ochiai Y, Nápoles OC, Valenti G, White RA, Belin BR, Zamechek LB, LaBella JS, Wang TC. Fu N, et al. Among authors: white ra. Cell Mol Gastroenterol Hepatol. 2021;11(4):1119-1138. doi: 10.1016/j.jcmgh.2020.11.007. Epub 2020 Nov 26. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33249238 Free PMC article.
Neuro-Mesenchymal Interaction Mediated by a β2-Adrenergic Nerve Growth Factor Feedforward Loop Promotes Colorectal Cancer Progression.
Kobayashi H, Iida T, Ochiai Y, Malagola E, Zhi X, White RA, Qian J, Wu F, Waterbury QT, Tu R, Zheng B, LaBella JS, Zamechek LB, Ogura A, Woods SL, Worthley DL, Enomoto A, Wang TC. Kobayashi H, et al. Among authors: white ra. Cancer Discov. 2025 Jan 13;15(1):202-226. doi: 10.1158/2159-8290.CD-24-0287. Cancer Discov. 2025. PMID: 39137067
Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis.
Jiang Z, Wu F, Laise P, Takayuki T, Na F, Kim W, Kobayashi H, Chang W, Takahashi R, Valenti G, Sunagawa M, White RA, Macchini M, Renz BW, Middelhoff M, Hayakawa Y, Dubeykovskaya ZA, Tan X, Chu TH, Nagar K, Tailor Y, Belin BR, Anand A, Asfaha S, Finlayson MO, Iuga AC, Califano A, Wang TC. Jiang Z, et al. Among authors: white ra. Cell Stem Cell. 2023 Aug 3;30(8):1091-1109.e7. doi: 10.1016/j.stem.2023.07.002. Cell Stem Cell. 2023. PMID: 37541213 Free PMC article.
Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.
Renz BW, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, Middelhoff MA, Ilmer M, Oberstein PE, Angele MK, Deng H, Hayakawa Y, Westphalen CB, Werner J, Remotti H, Reichert M, Tailor YH, Nagar K, Friedman RA, Iuga AC, Olive KP, Wang TC. Renz BW, et al. Among authors: white ra. Cancer Discov. 2018 Nov;8(11):1458-1473. doi: 10.1158/2159-8290.CD-18-0046. Epub 2018 Sep 5. Cancer Discov. 2018. PMID: 30185628 Free PMC article.
764 results