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332 results

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Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.
Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeño-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Pérez ÁJ, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS. Cluntun AA, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2024 Oct 8:2024.10.07.617073. doi: 10.1101/2024.10.07.617073. bioRxiv. 2024. PMID: 39416192 Free PMC article. Preprint.
Substrate identification and specificity profiling of deubiquitylases against endogenously-generated ubiquitin-protein conjugates.
Rossio V, Paulo JA, Liu X, Gygi SP, King RW. Rossio V, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Dec 20:2023.12.20.572581. doi: 10.1101/2023.12.20.572581. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Jul 18;31(7):1349-1362.e5. doi: 10.1016/j.chembiol.2024.05.001 PMID: 38187689 Free PMC article. Updated. Preprint.
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Mar 27:2023.03.27.534444. doi: 10.1101/2023.03.27.534444. bioRxiv. 2023. PMID: 37034684 Free PMC article. Preprint.
Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer.
DeAngelo SL, Zhao L, Dziechciarz S, Shin M, Solanki S, Balia A, El-Derany MO, Castillo C, Qin Y, Das NK, Bell HN, Paulo JA, Zhang Y, Rossiter NJ, McCulla EC, He J, Talukder I, Ng BW, Schafer ZT, Neamati N, Mancias JD, Koutmos M, Shah YM. DeAngelo SL, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2024 Aug 27:2024.03.29.587381. doi: 10.1101/2024.03.29.587381. bioRxiv. 2024. PMID: 38617233 Free PMC article. Preprint.
Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.
Lee JD, Menasche BL, Mavrikaki M, Uyemura MM, Hong SM, Kozlova N, Wei J, Alfajaro MM, Filler RB, Müller A, Saxena T, Posey RR, Cheung P, Muranen T, Heng YJ, Paulo JA, Wilen CB, Slack FJ. Lee JD, et al. Among authors: paulo ja. bioRxiv [Preprint]. 2023 Sep 1:2023.08.31.555625. doi: 10.1101/2023.08.31.555625. bioRxiv. 2023. Update in: Cell Rep. 2023 Dec 26;42(12):113478. doi: 10.1016/j.celrep.2023.113478 PMID: 37693555 Free PMC article. Updated. Preprint.
332 results