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FITM2 deficiency results in ER lipid accumulation, ER stress, and reduced apolipoprotein B lipidation and VLDL triglyceride secretion in vitro and in mouse liver.
Wang H, Nikain C, Fortounas KI, Amengual J, Tufanli O, La Forest M, Yu Y, Wang MC, Watts R, Lehner R, Qiu Y, Cai M, Kurland IJ, Goldberg IJ, Rajan S, Hussain MM, Brodsky JL, Fisher EA. Wang H, et al. Mol Metab. 2024 Oct 18:102048. doi: 10.1016/j.molmet.2024.102048. Online ahead of print. Mol Metab. 2024. PMID: 39426520 Free article.
FITM2 deficiency results in ER lipid accumulation, ER stress, reduced apolipoprotein B lipidation, and VLDL triglyceride secretion in vitro and in mouse liver.
Wang H, Nikain C, Amengual J, La Forest M, Yu Y, Wang MC, Watts R, Lehner R, Qiu Y, Cai M, Kurland IJ, Goldberg IJ, Rajan S, Hussain MM, Brodsky JL, Fisher EA. Wang H, et al. Among authors: rajan s. bioRxiv [Preprint]. 2023 Dec 7:2023.12.05.570183. doi: 10.1101/2023.12.05.570183. bioRxiv. 2023. Update in: Mol Metab. 2024 Oct 18:102048. doi: 10.1016/j.molmet.2024.102048. PMID: 38106013 Free PMC article. Updated. Preprint.
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
van Zwol W, Rimbert A, Wolters JC, Smit M, Bloks VW, Kloosterhuis NJ, Huijkman NCA, Koster MH, Tharehalli U, de Neck SM, Bournez C, Fuh MM, Kuipers J, Rajan S, de Bruin A, Ginsberg HN, van Westen GJP, Hussain MM, Scheja L, Heeren J, Zimmerman P, van de Sluis B, Kuivenhoven JA. van Zwol W, et al. Among authors: rajan s. Hepatology. 2023 Nov 1;78(5):1418-1432. doi: 10.1002/hep.32709. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36053190 Free PMC article.
1,369 results