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A high-throughput target-based screening approach for the identification and assessment of Mycobacterium tuberculosis mycothione reductase inhibitors.
Smiejkowska N, Oorts L, Van Calster K, De Vooght L, Geens R, Mattelaer H-P, Augustyns K, Strelkov SV, Lamprecht D, Temmerman K, Sterckx YG-J, Cappoen D, Cos P. Smiejkowska N, et al. Microbiol Spectr. 2024 Mar 5;12(3):e0372323. doi: 10.1128/spectrum.03723-23. Epub 2024 Feb 5. Microbiol Spectr. 2024. PMID: 38315026 Free PMC article.
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.
Saini V, Chinta KC, Reddy VP, Glasgow JN, Stein A, Lamprecht DA, Rahman MA, Mackenzie JS, Truebody BE, Adamson JH, Kunota TTR, Bailey SM, Moellering DR, Lancaster JR Jr, Steyn AJC. Saini V, et al. Among authors: lamprecht da. Nat Commun. 2020 Jan 28;11(1):557. doi: 10.1038/s41467-019-14132-y. Nat Commun. 2020. PMID: 31992699 Free PMC article.
Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis.
Saini V, Cumming BM, Guidry L, Lamprecht DA, Adamson JH, Reddy VP, Chinta KC, Mazorodze JH, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, Steyn AJC. Saini V, et al. Among authors: lamprecht da. Cell Rep. 2016 Jan 26;14(3):572-585. doi: 10.1016/j.celrep.2015.12.056. Epub 2016 Jan 7. Cell Rep. 2016. PMID: 26774486 Free PMC article.
Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c.
Moosa A, Lamprecht DA, Arora K, Barry CE 3rd, Boshoff HIM, Ioerger TR, Steyn AJC, Mizrahi V, Warner DF. Moosa A, et al. Among authors: lamprecht da. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e01338-17. doi: 10.1128/AAC.01338-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28760899 Free PMC article.
16 results