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Administration of broadly neutralizing anti-HIV-1 antibodies at ART initiation maintains long-term CD8+ T cell immunity.
Rosás-Umbert M, Gunst JD, Pahus MH, Olesen R, Schleimann M, Denton PW, Ramos V, Ward A, Kinloch NN, Copertino DC, Escribà T, Llano A, Brumme ZL, Brad Jones R, Mothe B, Brander C, Fox J, Nussenzweig MC, Fidler S, Caskey M, Tolstrup M, Søgaard OS. Rosás-Umbert M, et al. Among authors: gunst jd. Nat Commun. 2022 Oct 29;13(1):6473. doi: 10.1038/s41467-022-34171-2. Nat Commun. 2022. PMID: 36309514 Free PMC article.
Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial.
Gunst JD, Højen JF, Pahus MH, Rosás-Umbert M, Stiksrud B, McMahon JH, Denton PW, Nielsen H, Johansen IS, Benfield T, Leth S, Gerstoft J, Østergaard L, Schleimann MH, Olesen R, Støvring H, Vibholm L, Weis N, Dyrhol-Riise AM, Pedersen KBH, Lau JSY, Copertino DC Jr, Linden N, Huynh TT, Ramos V, Jones RB, Lewin SR, Tolstrup M, Rasmussen TA, Nussenzweig MC, Caskey M, Reikvam DH, Søgaard OS. Gunst JD, et al. Nat Med. 2023 Oct;29(10):2547-2558. doi: 10.1038/s41591-023-02547-6. Epub 2023 Sep 11. Nat Med. 2023. PMID: 37696935 Free PMC article. Clinical Trial.
Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial.
Gunst JD, Pahus MH, Rosás-Umbert M, Lu IN, Benfield T, Nielsen H, Johansen IS, Mohey R, Østergaard L, Klastrup V, Khan M, Schleimann MH, Olesen R, Støvring H, Denton PW, Kinloch NN, Copertino DC, Ward AR, Alberto WDC, Nielsen SD, Puertas MC, Ramos V, Reeves JD, Petropoulos CJ, Martinez-Picado J, Brumme ZL, Jones RB, Fox J, Tolstrup M, Nussenzweig MC, Caskey M, Fidler S, Søgaard OS. Gunst JD, et al. Nat Med. 2022 Nov;28(11):2424-2435. doi: 10.1038/s41591-022-02023-7. Epub 2022 Oct 17. Nat Med. 2022. PMID: 36253609 Free PMC article. Clinical Trial.
Immunomodulation with IL-7 and IL-15 in HIV-1 infection.
Gunst JD, Goonetilleke N, Rasmussen TA, Søgaard OS. Gunst JD, et al. J Virus Erad. 2023 Sep 5;9(3):100347. doi: 10.1016/j.jve.2023.100347. eCollection 2023 Sep. J Virus Erad. 2023. PMID: 37767312 Free PMC article.
Host Receptor Targeting to Treat Covid-19.
Gunst JD, Søgaard OS. Gunst JD, et al. NEJM Evid. 2023 Nov;2(11):EVIDe2300222. doi: 10.1056/EVIDe2300222. Epub 2023 Oct 24. NEJM Evid. 2023. PMID: 38320534
The impact of analytical treatment interruptions and trial interventions on time to viral re-suppression in people living with HIV restarting ART in cure-related clinical studies: a systematic review and meta-analysis.
Lee MJ, Eason M, Castagna A, Laura G, De Scheerder MA, Riley J, Tebas P, Gunst J, Søgaard O, Florence E, Kroon E, De Souza M, Mothe B, Caskey M, Fidler S. Lee MJ, et al. J Int AIDS Soc. 2024 Aug;27(8):e26349. doi: 10.1002/jia2.26349. J Int AIDS Soc. 2024. PMID: 39155436 Free PMC article.
38 results