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Page 1
Structure-Guided Discovery of Selective USP7 Inhibitors with In Vivo Activity.
Vasas A, Ivanschitz L, Molnár B, Kiss Á, Baker L, Fiumana A, Macias A, Murray JB, Sanders E, Whitehead N, Hubbard RE, Saunier C, Monceau E, Girard AM, Rousseau M, Chanrion M, Demarles D, Geneste O, Weber C, Lewkowicz E, Kotschy A. Vasas A, et al. Among authors: girard am. J Med Chem. 2024 Oct 23. doi: 10.1021/acs.jmedchem.4c01472. Online ahead of print. J Med Chem. 2024. PMID: 39441669
Tissue-Like 3D Standard and Protocols for Microscope Quality Management.
Abrams B, Pengo T, Wee TL, Deagle RC, Vuillemin N, Callahan LM, Smith MA, Kubow KE, Girard AM, Rappoport JZ, Bayles CJ, Cameron LA, Cole R, Brown CM. Abrams B, et al. Among authors: girard am. Microsc Microanal. 2023 Apr 5;29(2):616-634. doi: 10.1093/micmic/ozad014. Microsc Microanal. 2023. PMID: 37749742 Free PMC article.
Evaluation of a Wastewater-Based Epidemiological Approach to Estimate the Prevalence of SARS-CoV-2 Infections and the Detection of Viral Variants in Disparate Oregon Communities at City and Neighborhood Scales.
Layton BA, Kaya D, Kelly C, Williamson KJ, Alegre D, Bachhuber SM, Banwarth PG, Bethel JW, Carter K, Dalziel BD, Dasenko M, Geniza M, George A, Girard AM, Haggerty R, Higley KA, Hynes DM, Lubchenco J, McLaughlin KR, Nieto FJ, Noakes A, Peterson M, Piemonti AD, Sanders JL, Tyler BM, Radniecki TS. Layton BA, et al. Among authors: girard am. Environ Health Perspect. 2022 Jun;130(6):67010. doi: 10.1289/EHP10289. Epub 2022 Jun 29. Environ Health Perspect. 2022. PMID: 35767012 Free PMC article.
Discovery of S64315, a Potent and Selective Mcl-1 Inhibitor.
Szlavik Z, Csekei M, Paczal A, Szabo ZB, Sipos S, Radics G, Proszenyak A, Balint B, Murray J, Davidson J, Chen I, Dokurno P, Surgenor AE, Daniels ZM, Hubbard RE, Le Toumelin-Braizat G, Claperon A, Lysiak-Auvity G, Girard AM, Bruno A, Chanrion M, Colland F, Maragno AL, Demarles D, Geneste O, Kotschy A. Szlavik Z, et al. Among authors: girard am. J Med Chem. 2020 Nov 25;63(22):13762-13795. doi: 10.1021/acs.jmedchem.0c01234. Epub 2020 Nov 4. J Med Chem. 2020. PMID: 33146521
S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth.
Casara P, Davidson J, Claperon A, Le Toumelin-Braizat G, Vogler M, Bruno A, Chanrion M, Lysiak-Auvity G, Le Diguarher T, Starck JB, Chen I, Whitehead N, Graham C, Matassova N, Dokurno P, Pedder C, Wang Y, Qiu S, Girard AM, Schneider E, Gravé F, Studeny A, Guasconi G, Rocchetti F, Maïga S, Henlin JM, Colland F, Kraus-Berthier L, Le Gouill S, Dyer MJS, Hubbard R, Wood M, Amiot M, Cohen GM, Hickman JA, Morris E, Murray J, Geneste O. Casara P, et al. Among authors: girard am. Oncotarget. 2018 Apr 13;9(28):20075-20088. doi: 10.18632/oncotarget.24744. eCollection 2018 Apr 13. Oncotarget. 2018. PMID: 29732004 Free PMC article.
Next-Generation Magnetic Nanocomposites: Cytotoxic and Genotoxic Effects of Coated and Uncoated Ferric Cobalt Boron (FeCoB) Nanoparticles In Vitro.
Netzer K, Jordakieva G, Girard AM, Budinsky AC, Pilger A, Richter L, Kataeva N, Schotter J, Godnic-Cvar J, Ertl P. Netzer K, et al. Among authors: girard am. Basic Clin Pharmacol Toxicol. 2018 Mar;122(3):355-363. doi: 10.1111/bcpt.12918. Epub 2017 Nov 21. Basic Clin Pharmacol Toxicol. 2018. PMID: 28990335 Free article.
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
Kotschy A, Szlavik Z, Murray J, Davidson J, Maragno AL, Le Toumelin-Braizat G, Chanrion M, Kelly GL, Gong JN, Moujalled DM, Bruno A, Csekei M, Paczal A, Szabo ZB, Sipos S, Radics G, Proszenyak A, Balint B, Ondi L, Blasko G, Robertson A, Surgenor A, Dokurno P, Chen I, Matassova N, Smith J, Pedder C, Graham C, Studeny A, Lysiak-Auvity G, Girard AM, Gravé F, Segal D, Riffkin CD, Pomilio G, Galbraith LC, Aubrey BJ, Brennan MS, Herold MJ, Chang C, Guasconi G, Cauquil N, Melchiore F, Guigal-Stephan N, Lockhart B, Colland F, Hickman JA, Roberts AW, Huang DC, Wei AH, Strasser A, Lessene G, Geneste O. Kotschy A, et al. Among authors: girard am. Nature. 2016 Oct 27;538(7626):477-482. doi: 10.1038/nature19830. Epub 2016 Oct 19. Nature. 2016. PMID: 27760111
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