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BLU-945, a potent and selective next-generation EGFR TKI, has antitumor activity in models of osimertinib-resistant non-small-cell lung cancer.
Lim SM, Schalm SS, Lee EJ, Park S, Conti C, Millet YA, Woessner R, Zhang Z, Tavera-Mendoza LE, Stevison F, Albayya F, Dineen TA, Hsieh J, Oh SY, Zalutskaya A, Rotow J, Goto K, Lee DH, Yun MR, Cho BC. Lim SM, et al. Among authors: schalm ss. Ther Adv Med Oncol. 2024 Oct 21;16:17588359241280689. doi: 10.1177/17588359241280689. eCollection 2024. Ther Adv Med Oncol. 2024. PMID: 39444426 Free PMC article.
Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma.
Schalm SS, O'Hearn E, Wilson K, LaBranche TP, Silva G, Zhang Z, DiPietro L, Bifulco N, Woessner R, Stransky N, Sappal D, Campbell R, Lobbardi R, Palmer M, Kim J, Ye C, Dorsch M, Lengauer C, Guzi T, Kadambi V, Garner A, Hoeflich KP. Schalm SS, et al. Gastro Hep Adv. 2022 Nov 8;2(3):307-321. doi: 10.1016/j.gastha.2022.11.004. eCollection 2023. Gastro Hep Adv. 2022. PMID: 39132655 Free PMC article.
KT-253, A Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy Than MDM2 Small Molecule Inhibitors.
Chutake YK, Mayo MF, Dumont N, Filiatrault J, Breitkopf SB, Cho P, Chen D, Dixit VS, Proctor WR, Kuhn EW, Bollinger Martinez S, McDonald AA, Qi J, Hu KN, Karnik R, Growney JD, Sharma K, Schalm SS, Gollerkeri AM, Mainolfi N, Williams JA, Weiss MM. Chutake YK, et al. Among authors: schalm ss. Mol Cancer Ther. 2024 Dec 9. doi: 10.1158/1535-7163.MCT-24-0306. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39648478
Proteolytic processing of protocadherin proteins requires endocytosis.
Buchanan SM, Schalm SS, Maniatis T. Buchanan SM, et al. Among authors: schalm ss. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17774-9. doi: 10.1073/pnas.1013105107. Epub 2010 Sep 27. Proc Natl Acad Sci U S A. 2010. PMID: 20876099 Free PMC article.
PI3-kinase and TOR: PIKTORing cell growth.
Richardson CJ, Schalm SS, Blenis J. Richardson CJ, et al. Among authors: schalm ss. Semin Cell Dev Biol. 2004 Apr;15(2):147-59. doi: 10.1016/j.semcdb.2003.12.023. Semin Cell Dev Biol. 2004. PMID: 15209374 Review.
12 results