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Engineered AAV capsid transport mutants overcome transduction deficiencies in the aged CNS.
Sandoval IM, Kelley CM, Bernal-Conde LD, Steece-Collier K, Marmion DJ, Davidsson M, Crosson SM, Boye SL, Boye SE, Manfredsson FP. Sandoval IM, et al. Among authors: davidsson m. Mol Ther Nucleic Acids. 2024 Sep 12;35(4):102332. doi: 10.1016/j.omtn.2024.102332. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39445231 Free PMC article.
A comparison of machine learning approaches for the quantification of microglial cells in the brain of mice, rats and non-human primates.
Anwer DM, Gubinelli F, Kurt YA, Sarauskyte L, Jacobs F, Venuti C, Sandoval IM, Yang Y, Stancati J, Mazzocchi M, Brandi E, O'Keeffe G, Steece-Collier K, Li JY, Deierborg T, Manfredsson FP, Davidsson M, Heuer A. Anwer DM, et al. Among authors: davidsson m. PLoS One. 2023 May 1;18(5):e0284480. doi: 10.1371/journal.pone.0284480. eCollection 2023. PLoS One. 2023. PMID: 37126506 Free PMC article.
Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits.
Negrini M, Tomasello G, Davidsson M, Fenyi A, Adant C, Hauser S, Espa E, Gubinelli F, Manfredsson FP, Melki R, Heuer A. Negrini M, et al. Among authors: davidsson m. J Parkinsons Dis. 2022;12(4):1133-1153. doi: 10.3233/JPD-212555. J Parkinsons Dis. 2022. PMID: 35213388 Free PMC article.
Lateralized deficits after unilateral AAV-vector based overexpression of alpha-synuclein in the midbrain of rats on drug-free behavioral tests.
Gubinelli F, Cazzolla G, Negrini M, Kulacz I, Mehrdadian A, Tomasello G, Venuti C, Sarauskyte L, Jacobs F, Manfredsson FP, Davidsson M, Heuer A. Gubinelli F, et al. Among authors: davidsson m. Behav Brain Res. 2022 Jul 5;429:113887. doi: 10.1016/j.bbr.2022.113887. Epub 2022 Apr 8. Behav Brain Res. 2022. PMID: 35405174 Free article.
Destabilizing Domains Enable Long-Term and Inert Regulation of GDNF Expression in the Brain.
Quintino L, Namislo A, Davidsson M, Breger LS, Kavanagh P, Avallone M, Elgstrand-Wettergren E, Isaksson C, Lundberg C. Quintino L, et al. Among authors: davidsson m. Mol Ther Methods Clin Dev. 2018 Sep 4;11:29-39. doi: 10.1016/j.omtm.2018.08.008. eCollection 2018 Dec 14. Mol Ther Methods Clin Dev. 2018. PMID: 30324128 Free PMC article.
31 results