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Microglia regulate cortical remyelination via TNFR1-dependent phenotypic polarization.
Boutou A, Roufagalas I, Politopoulou K, Tastsoglou S, Abouzeid M, Skoufos G, Verdu de Juan L, Ko JH, Kyrargyri V, Hatzigeorgiou AG, Barnum CJ, Tesi RJ, Bauer J, Lassmann H, Johnson MR, Probert L. Boutou A, et al. Among authors: probert l. Cell Rep. 2024 Nov 26;43(11):114894. doi: 10.1016/j.celrep.2024.114894. Epub 2024 Oct 23. Cell Rep. 2024. PMID: 39446583 Free article.
IKKβ deletion from CNS macrophages increases neuronal excitability and accelerates the onset of EAE, while from peripheral macrophages reduces disease severity.
Avloniti M, Evangelidou M, Gomini M, Loupis T, Emmanouil M, Mitropoulou A, Tselios T, Lassmann H, Gruart A, Delgado-García JM, Probert L, Kyrargyri V. Avloniti M, et al. Among authors: probert l. J Neuroinflammation. 2024 Jan 27;21(1):34. doi: 10.1186/s12974-024-03023-9. J Neuroinflammation. 2024. PMID: 38279130 Free PMC article.
Spontaneous human CD8 T cell and autoimmune encephalomyelitis-induced CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB1*15-positive multiple sclerosis humanized immune system mice.
Papazian I, Kourouvani M, Dagkonaki A, Gouzouasis V, Dimitrakopoulou L, Markoglou N, Badounas F, Tselios T, Anagnostouli M, Probert L. Papazian I, et al. Among authors: probert l. Elife. 2024 Jun 20;12:RP88826. doi: 10.7554/eLife.88826. Elife. 2024. PMID: 38900149 Free PMC article.
A National Representative, Cross-Sectional Study by the Hellenic Academy of NeuroImmunology (HEL.A.NI.) on COVID-19 and Multiple Sclerosis: Overall Impact and Willingness Toward Vaccination.
Boziki M, Styliadis C, Bakirtzis C, Grigoriadou E, Sintila AS, Nikolaidis I, Vrienniou A, Geys L, Pelidou SH, Probert L, Papazisis G, Bamidis P, Grigoriadis N. Boziki M, et al. Among authors: probert l. Front Neurol. 2021 Nov 25;12:757038. doi: 10.3389/fneur.2021.757038. eCollection 2021. Front Neurol. 2021. PMID: 34899577 Free PMC article.
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice.
Papazian I, Tsoukala E, Boutou A, Karamita M, Kambas K, Iliopoulou L, Fischer R, Kontermann RE, Denis MC, Kollias G, Lassmann H, Probert L. Papazian I, et al. Among authors: probert l. J Neuroinflammation. 2021 Sep 26;18(1):222. doi: 10.1186/s12974-021-02200-4. J Neuroinflammation. 2021. PMID: 34565380 Free PMC article.
Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology.
Stergiou IE, Kambas K, Poulaki A, Giannouli S, Katsila T, Dimitrakopoulou A, Vidali V, Mouchtouris V, Kloukina I, Xingi E, Pagakis SN, Probert L, Patrinos GP, Ritis K, Tzioufas AG, Voulgarelis M. Stergiou IE, et al. Among authors: probert l. Int J Mol Sci. 2021 Apr 15;22(8):4099. doi: 10.3390/ijms22084099. Int J Mol Sci. 2021. PMID: 33921064 Free PMC article.
Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions.
Dagkonaki A, Avloniti M, Evangelidou M, Papazian I, Kanistras I, Tseveleki V, Lampros F, Tselios T, Jensen LT, Möbius W, Ruhwedel T, Androutsou ME, Matsoukas J, Anagnostouli M, Lassmann H, Probert L. Dagkonaki A, et al. Among authors: probert l. Front Immunol. 2020 Nov 19;11:575451. doi: 10.3389/fimmu.2020.575451. eCollection 2020. Front Immunol. 2020. PMID: 33329540 Free PMC article.
93 results