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Page 1
Aspartate signalling drives lung metastasis via alternative translation.
Doglioni G, Fernández-García J, Igelmann S, Altea-Manzano P, Blomme A, La Rovere R, Liu XZ, Liu Y, Tricot T, Nobis M, An N, Leclercq M, El Kharraz S, Karras P, Hsieh YH, Solari FA, Martins Nascentes Melo L, Allies G, Scopelliti A, Rossi M, Vermeire I, Broekaert D, Ferreira Campos AM, Neven P, Maetens M, Van Baelen K, Alkan HF, Planque M, Floris G, Sickmann A, Tasdogan A, Marine JC, Scheele CLGJ, Desmedt C, Bultynck G, Close P, Fendt SM. Doglioni G, et al. Among authors: allies g. Nature. 2025 Jan 1. doi: 10.1038/s41586-024-08335-7. Online ahead of print. Nature. 2025. PMID: 39743589
Selenoprotein O Promotes Melanoma Metastasis and Regulates Mitochondrial Complex II Activity.
Nascentes Melo LM, Sabatier M, Ramesh V, Szylo KJ, Fraser CS, Pon A, Mitchell EC, Servage KA, Allies G, Westedt IV, Cansiz F, Krystkiewicz J, Kutritz A, Schadendorf D, Morrison SJ, Ubellacker JM, Sreelatha A, Tasdogan A. Nascentes Melo LM, et al. Among authors: allies g. Cancer Res. 2024 Dec 19. doi: 10.1158/0008-5472.CAN-23-2194. Online ahead of print. Cancer Res. 2024. PMID: 39700395
Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.
Shelton SD, House S, Martins Nascentes Melo L, Ramesh V, Chen Z, Wei T, Wang X, Llamas CB, Venigalla SSK, Menezes CJ, Allies G, Krystkiewicz J, Rösler J, Meckelmann SW, Zhao P, Rambow F, Schadendorf D, Zhao Z, Gill JG, DeBerardinis RJ, Morrison SJ, Tasdogan A, Mishra P. Shelton SD, et al. Among authors: allies g. Sci Adv. 2024 Nov;10(44):eadk8801. doi: 10.1126/sciadv.adk8801. Epub 2024 Nov 1. Sci Adv. 2024. PMID: 39485847 Free PMC article.
Retrotransposons are co-opted to activate hematopoietic stem cells and erythropoiesis.
Phan J, Chen B, Zhao Z, Allies G, Iannaccone A, Paul A, Cansiz F, Spina A, Leven AS, Gellhaus A, Schadendorf D, Kimmig R, Mettlen M, Tasdogan A, Morrison SJ. Phan J, et al. Among authors: allies g. Science. 2024 Nov 8;386(6722):eado6836. doi: 10.1126/science.ado6836. Epub 2024 Nov 8. Science. 2024. PMID: 39446896
Short-term post-fast refeeding enhances intestinal stemness via polyamines.
Imada S, Khawaled S, Shin H, Meckelmann SW, Whittaker CA, Corrêa RO, Alquati C, Lu Y, Tie G, Pradhan D, Calibasi-Kocal G, Nascentes Melo LM, Allies G, Rösler J, Wittenhofer P, Krystkiewicz J, Schmitz OJ, Roper J, Vinolo MAR, Ricciardiello L, Lien EC, Vander Heiden MG, Shivdasani RA, Cheng CW, Tasdogan A, Yilmaz ÖH. Imada S, et al. Among authors: allies g. Nature. 2024 Sep;633(8031):895-904. doi: 10.1038/s41586-024-07840-z. Epub 2024 Aug 21. Nature. 2024. PMID: 39169180
Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation.
Rogava M, Aprati TJ, Chi WY, Melms JC, Hug C, Davis SH, Earlie EM, Chung C, Deshmukh SK, Wu S, Sledge G, Tang S, Ho P, Amin AD, Caprio L, Gurjao C, Tagore S, Ngo B, Lee MJ, Zanetti G, Wang Y, Chen S, Ge W, Melo LMN, Allies G, Rösler J, Gibney GT, Schmitz OJ, Sykes M, Creusot RJ, Tüting T, Schadendorf D, Röcken M, Eigentler TK, Molotkov A, Mintz A, Bakhoum SF, Beyaz S, Cantley LC, Sorger PK, Meckelmann SW, Tasdogan A, Liu D, Laughney AM, Izar B. Rogava M, et al. Among authors: allies g. Nat Cancer. 2024 Mar;5(3):433-447. doi: 10.1038/s43018-023-00704-x. Epub 2024 Jan 29. Nat Cancer. 2024. PMID: 38286827 Free PMC article.
Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis.
Imada S, Shin H, Khawaled S, Meckelmann SW, Whittaker CA, Corrêa RO, Pradhan D, Calibasi-Kocal G, Melo LMN, Allies G, Wittenhofer P, Schmitz OJ, Roper J, Vinolo MAR, Cheng CW, Tasdogan A, Yilmaz ÖH. Imada S, et al. Among authors: allies g. Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2320717. doi: 10.21203/rs.3.rs-2320717/v1. Res Sq. 2023. Update in: Nature. 2024 Sep;633(8031):895-904. doi: 10.1038/s41586-024-07840-z PMID: 36711807 Free PMC article. Updated. Preprint.
Autoreactive antibodies control blood glucose by regulating insulin homeostasis.
Amendt T, Allies G, Nicolò A, El Ayoubi O, Young M, Röszer T, Setz CS, Warnatz K, Jumaa H. Amendt T, et al. Among authors: allies g. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2115695119. doi: 10.1073/pnas.2115695119. Proc Natl Acad Sci U S A. 2022. PMID: 35131852 Free PMC article.
Primary Immune Responses and Affinity Maturation Are Controlled by IgD.
Amendt T, Ayoubi OE, Linder AT, Allies G, Young M, Setz CS, Jumaa H. Amendt T, et al. Among authors: allies g. Front Immunol. 2021 Aug 9;12:709240. doi: 10.3389/fimmu.2021.709240. eCollection 2021. Front Immunol. 2021. PMID: 34434193 Free PMC article.
DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization.
Tasdogan A, Kumar S, Allies G, Bausinger J, Beckel F, Hofemeister H, Mulaw M, Madan V, Scharffetter-Kochanek K, Feuring-Buske M, Doehner K, Speit G, Stewart AF, Fehling HJ. Tasdogan A, et al. Among authors: allies g. Cell Stem Cell. 2017 Mar 2;20(3):415. doi: 10.1016/j.stem.2017.02.002. Cell Stem Cell. 2017. PMID: 28257711 Free article. No abstract available.
13 results