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Page 1
CCL2 blockade combined with PD-1/P-selectin immunomodulators impedes breast cancer brain metastasis.
Israeli Dangoor S, Khoury R, Salomon K, Pozzi S, Shahar S, Miari A, Leichtmann-Bardoogo Y, Bar-Hai N, Frommer N, Yeini E, Winkler T, Balint Lahat N, Kamer I, Hadad O, Laue K, Brem H, Hyde TM, Bar J, Barshack I, Ben-David U, Ishay-Ronen D, Maoz BM, Satchi-Fainaro R. Israeli Dangoor S, et al. Among authors: ben david u. Brain. 2024 Oct 25:awae347. doi: 10.1093/brain/awae347. Online ahead of print. Brain. 2024. PMID: 39450648
The effect of non-oncology drugs on clinical and genomic risk in early luminal breast cancer.
Waissengrin B, Zahavi T, Salmon-Divon M, Goldberg A, Wolf I, Rubinek T, Winkler T, Farkash O, Grinshpun A, Zubkov A, Khatib M, Shachar SS, Keren N, Carmi-Levy I, Ben-David U, Sonnenblick A. Waissengrin B, et al. ESMO Open. 2022 Dec;7(6):100648. doi: 10.1016/j.esmoop.2022.100648. Epub 2022 Nov 30. ESMO Open. 2022. PMID: 36462463 Free PMC article.
Acute expression of human APOBEC3B in mice results in RNA editing and lethality.
Alonso de la Vega A, Temiz NA, Tasakis R, Somogyi K, Salgueiro L, Zimmer E, Ramos M, Diaz-Jimenez A, Chocarro S, Fernández-Vaquero M, Stefanovska B, Reuveni E, Ben-David U, Stenzinger A, Poth T, Heikenwälder M, Papavasiliou N, Harris RS, Sotillo R. Alonso de la Vega A, et al. Genome Biol. 2023 Nov 24;24(1):267. doi: 10.1186/s13059-023-03115-4. Genome Biol. 2023. PMID: 38001542 Free PMC article.
Aneuploidy as a driver of human cancer.
Sdeor E, Okada H, Saad R, Ben-Yishay T, Ben-David U. Sdeor E, et al. Among authors: ben david u. Nat Genet. 2024 Oct;56(10):2014-2026. doi: 10.1038/s41588-024-01916-2. Epub 2024 Oct 2. Nat Genet. 2024. PMID: 39358600 Review.
Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage.
Zerbib J, Ippolito MR, Eliezer Y, De Feudis G, Reuveni E, Savir Kadmon A, Martin S, Viganò S, Leor G, Berstler J, Muenzner J, Mülleder M, Campagnolo EM, Shulman ED, Chang T, Rubolino C, Laue K, Cohen-Sharir Y, Scorzoni S, Taglietti S, Ratti A, Stossel C, Golan T, Nicassio F, Ruppin E, Ralser M, Vazquez F, Ben-David U, Santaguida S. Zerbib J, et al. Among authors: ben david u. Nat Commun. 2024 Sep 9;15(1):7772. doi: 10.1038/s41467-024-52176-x. Nat Commun. 2024. PMID: 39251587 Free PMC article.
Increased RNA and protein degradation is required for counteracting transcriptional burden and proteotoxic stress in human aneuploid cells.
Ippolito MR, Zerbib J, Eliezer Y, Reuveni E, Vigano S, De Feudis G, Shulman ED, Savir Kadmon A, Slutsky R, Chang T, Campagnolo EM, Taglietti S, Scorzoni S, Gianotti S, Martin S, Muenzner J, Mulleder M, Rozenblum N, Rubolino C, Ben-Yishay T, Laue K, Cohen-Sharir Y, Vigorito I, Nicassio F, Ruppin E, Ralser M, Vazquez F, Santaguida S, Ben-David U. Ippolito MR, et al. Among authors: ben david u. Cancer Discov. 2024 Sep 9. doi: 10.1158/2159-8290.CD-23-0309. Online ahead of print. Cancer Discov. 2024. PMID: 39247952
A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements.
Martin S, Scorzoni S, Cordone S, Mazzagatti A, Beznoussenko GV, Gunn AL, Di Bona M, Eliezer Y, Leor G, Ben-Yishay T, Loffreda A, Cancila V, Rainone MC, Ippolito MR, Martis V, Bedin F, Garrè M, Vaites LP, Vasapolli P, Polo S, Parazzoli D, Tripodo C, Mironov AA, Cuomo A, Ben-David U, Bakhoum SF, Hatch EM, Ly P, Santaguida S. Martin S, et al. Among authors: ben david u. Science. 2024 Aug 30;385(6712):eadj7446. doi: 10.1126/science.adj7446. Epub 2024 Aug 30. Science. 2024. PMID: 39208097
Chromosome 7 Gain Compensates for Chromosome 10 Loss in Glioma.
Nair NU, Schäffer AA, Gertz EM, Cheng K, Zerbib J, Sahu AD, Leor G, Shulman ED, Aldape KD, Ben-David U, Ruppin E. Nair NU, et al. Among authors: ben david u. Cancer Res. 2024 Oct 15;84(20):3464-3477. doi: 10.1158/0008-5472.CAN-24-1366. Cancer Res. 2024. PMID: 39078448
70 results