Link A - Search Results

1

Targeting PARP-1 and DNA Damage Response Defects in Colorectal Cancer Chemotherapy with Established and Novel PARP Inhibitors.

Demuth P, Thibol L, Lemsch A, Potlitz F, Schulig L, Grathwol C, Manolikakes G, Schade D, Roukos V, Link A, Fahrer J. Demuth P, et al. Among authors: link a. Cancers (Basel). 2024 Oct 10;16(20):3441. doi: 10.3390/cancers16203441. Cancers (Basel). 2024. PMID: 39456536 Free PMC article.

2

Correlation Analysis of Protein Expression of 10 HDAC/Sirtuin Isoenzymes with Sensitivities of 23 Anticancer Drugs in 17 Cancer Cell Lines and Potentiation of Drug Activity by Co-Treatment with HDAC Inhibitors.

Behnisch-Cornwell S, Grathwol CW, Schulig L, Voigt A, Baecker D, Link A, Bednarski PJ. Behnisch-Cornwell S, et al. Among authors: link a. Cancers (Basel). 2021 Dec 31;14(1):187. doi: 10.3390/cancers14010187. Cancers (Basel). 2021. PMID: 35008351 Free PMC article.

3

Advances in the discovery of new chemotypes through ultra-large library docking.

Potlitz F, Link A, Schulig L. Potlitz F, et al. Among authors: link a. Expert Opin Drug Discov. 2023 Mar;18(3):303-313. doi: 10.1080/17460441.2023.2171984. Epub 2023 Feb 2. Expert Opin Drug Discov. 2023. PMID: 36714919 Review.

4

Activation of Sirtuin 2 Inhibitors Employing Photoswitchable Geometry and Aqueous Solubility.

Grathwol CW, Wössner N, Behnisch-Cornwell S, Schulig L, Zhang L, Einsle O, Jung M, Link A. Grathwol CW, et al. Among authors: link a. ChemMedChem. 2020 Aug 5;15(15):1480-1489. doi: 10.1002/cmdc.202000148. Epub 2020 May 7. ChemMedChem. 2020. PMID: 32314517 Free PMC article.

5

A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction.

Potlitz F, Palm GJ, Bodtke A, Lammers M, Schade D, Link A. Potlitz F, et al. Among authors: link a. Molecules. 2024 Jun 27;29(13):3064. doi: 10.3390/molecules29133064. Molecules. 2024. PMID: 38999014 Free PMC article.

6

Interconnection of sulfides and sulfoxides in medicinal chemistry.

Surur AS, Schulig L, Link A. Surur AS, et al. Among authors: link a. Arch Pharm (Weinheim). 2019 Jan;352(1):e1800248. doi: 10.1002/ardp.201800248. Epub 2018 Dec 6. Arch Pharm (Weinheim). 2019. PMID: 30521146 Review.

7

Tetrahydroindoles as Multipurpose Screening Compounds and Novel Sirtuin Inhibitors.

Vojacek S, Schulig L, Wössner N, Geist N, Langel W, Jung M, Schade D, Link A. Vojacek S, et al. Among authors: link a. ChemMedChem. 2019 Apr 17;14(8):853-864. doi: 10.1002/cmdc.201900054. Epub 2019 Mar 21. ChemMedChem. 2019. PMID: 30811852

8

Replacing the oxidation-sensitive triaminoaryl chemotype of problematic K_V 7 channel openers: Exploration of a nicotinamide scaffold.

Wurm KW, Bartz FM, Schulig L, Bodtke A, Bednarski PJ, Link A. Wurm KW, et al. Among authors: link a. Arch Pharm (Weinheim). 2023 Feb;356(2):e2200473. doi: 10.1002/ardp.202200473. Epub 2022 Nov 17. Arch Pharm (Weinheim). 2023. PMID: 36395379

9

Expanding the Chemical Space of Transforming Growth Factor-β (TGFβ) Receptor Type II Degraders with 3,4-Disubstituted Indole Derivatives.

Längle D, Wojtowicz-Piotrowski S, Priegann T, Keller N, Wesseler F, Reckzeh ES, Steffens K, Grathwol C, Lemke J, Flasshoff M, Näther C, Jonson AC, Link A, Koch O, Di Guglielmo GM, Schade D. Längle D, et al. Among authors: link a. ACS Pharmacol Transl Sci. 2024 Mar 21;7(4):1069-1085. doi: 10.1021/acsptsci.3c00371. eCollection 2024 Apr 12. ACS Pharmacol Transl Sci. 2024. PMID: 38633593

10

Subcritical Fluid Chromatography at Sub-Ambient Temperatures for the Chiral Resolution of Ketamine Metabolites with Rapid-Onset Antidepressant Effects.

Hofstetter RK, Potlitz F, Schulig L, Kim S, Hasan M, Link A. Hofstetter RK, et al. Among authors: link a. Molecules. 2019 May 19;24(10):1927. doi: 10.3390/molecules24101927. Molecules. 2019. PMID: 31109124 Free PMC article.

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