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Page 1
Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B cell neoplasias.
Guerrero-Murillo M, Rill-Hinarejos A, Trincado JL, Bataller A, Ortiz-Maldonado V, Benítez-Ribas D, Español-Rego M, González-Navarro EA, Martínez-Cibrián N, Marchese D, Martín-Martín L, Martín García-Sancho A, Rives S, Heyn H, Juan M, Urbano-Ispizúa Á, Delgado J, Orfao A, Mereu E, Bueno C, Menendez P. Guerrero-Murillo M, et al. Among authors: menendez p. Cell Rep Med. 2024 Nov 19;5(11):101803. doi: 10.1016/j.xcrm.2024.101803. Epub 2024 Oct 28. Cell Rep Med. 2024. PMID: 39471818 Free PMC article.
TIM3, a human acute myeloid leukemia stem cell marker, does not enrich for leukemia-initiating stem cells in B-cell acute lymphoblastic leukemia.
Bueno C, Martínez A, Romecin PA, Zanetti SR, Tirtakusuma R, Genesca E, Camós M, Ramírez-Orellana M, Anguita E, Ballerini P, Locatelli F, Fuster JL, Menéndez P. Bueno C, et al. Among authors: menendez p. Haematologica. 2023 Aug 1;108(8):2229-2233. doi: 10.3324/haematol.2022.282394. Haematologica. 2023. PMID: 36655434 Free PMC article. No abstract available.
A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.
Bueno C, Torres-Ruiz R, Velasco-Hernandez T, Molina O, Petazzi P, Martinez A, Rodriguez V, Vinyoles M, Cantilena S, Williams O, Vega-Garcia N, Rodriguez-Perales S, Segovia JC, Quintana-Bustamante O, Roy A, Meyer C, Marschalek R, Smith AL, Milne TA, Fraga MF, Tejedor JR, Menéndez P. Bueno C, et al. Among authors: menendez p. Blood. 2023 Nov 16;142(20):1752-1756. doi: 10.1182/blood.2023020858. Blood. 2023. PMID: 37756522 Free article.
The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP).
Velasco P, Bautista F, Rubio A, Aguilar Y, Rives S, Dapena JL, Pérez A, Ramirez M, Saiz-Ladera C, Izquierdo E, Escudero A, Camós M, Vega-García N, Ortega M, Hidalgo-Gómez G, Palacio C, Menéndez P, Bueno C, Montero J, Romecín PA, Zazo S, Alvarez F, Parras J, Ortega-Sabater C, Chulián S, Rosa M, Cirillo D, García E, García J, Manzano-Muñoz A, Minguela A, Fuster JL. Velasco P, et al. Among authors: menendez p. Front Pediatr. 2023 Sep 20;11:1269560. doi: 10.3389/fped.2023.1269560. eCollection 2023. Front Pediatr. 2023. PMID: 37800011 Free PMC article.
Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression.
Molina O, Ortega-Sabater C, Thampi N, Fernández-Fuentes N, Guerrero-Murillo M, Martínez-Moreno A, Vinyoles M, Velasco-Hernández T, Bueno C, Trincado JL, Granada I, Campos D, Giménez C, Boer JM, den Boer ML, Calvo GF, Camós M, Fuster JL, Velasco P, Ballerini P, Locatelli F, Mullighan CG, Spierings DCJ, Foijer F, Pérez-García VM, Menéndez P. Molina O, et al. Among authors: menendez p. EMBO Mol Med. 2024 Jan;16(1):64-92. doi: 10.1038/s44321-023-00006-w. Epub 2023 Dec 15. EMBO Mol Med. 2024. PMID: 38177531 Free PMC article.
Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo.
Díez-Alonso L, Falgas A, Arroyo-Ródenas J, Romencín PA, Martínez A, Gómez-Rosel M, Blanco B, Jiménez-Reinoso A, Mayado A, Pérez-Pons A, Aguilar-Sopeña Ó, Ramírez-Fernández Á, Segura-Tudela A, Perez-Amill L, Tapia-Galisteo A, Domínguez-Alonso C, Rubio-Pérez L, Jara M, Solé F, Hangiu O, Almagro L, Albitre Á, Penela P, Sanz L, Anguita E, Valeri A, García-Ortiz A, Río P, Juan M, Martínez-López J, Roda-Navarro P, Martín-Antonio B, Orfao A, Menéndez P, Bueno C, Álvarez-Vallina L. Díez-Alonso L, et al. Among authors: menendez p. Sci Transl Med. 2024 Feb 14;16(734):eadg7962. doi: 10.1126/scitranslmed.adg7962. Epub 2024 Feb 14. Sci Transl Med. 2024. PMID: 38354229
Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells.
Velasco-Hernandez T, Trincado JL, Vinyoles M, Closa A, Martínez-Moreno A, Gutiérrez-Agüera F, Molina O, Rodríguez-Cortez VC, Ximeno-Parpal P, Fernández-Fuentes N, Petazzi P, Beneyto-Calabuig S, Velten L, Romecin P, Casquero R, Abollo-Jiménez F, de la Guardia RD, Lorden P, Bataller A, Lapillonne H, Stam RW, Vives S, Torrebadell M, Fuster JL, Bueno C, Sarry JE, Eyras E, Heyn H, Menéndez P. Velasco-Hernandez T, et al. Among authors: menendez p. Hemasphere. 2024 Feb 26;8(2):e45. doi: 10.1002/hem3.45. eCollection 2024 Feb. Hemasphere. 2024. PMID: 38435427 Free PMC article.
NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression.
Lopez-Millan B, Rubio-Gayarre A, Vinyoles M, Trincado JL, Fraga MF, Fernandez-Fuentes N, Guerrero-Murillo M, Martinez A, Velasco-Hernandez T, Falgàs A, Panisello C, Valcarcel G, Sardina JL, López-Martí P, Javierre BM, Del Valle-Pérez B, García de Herreros A, Locatelli F, Pieters R, Bardini M, Cazzaniga G, Rodríguez-Manzaneque JC, Hanewald T, Marschalek R, Milne TA, Stam RW, Tejedor JR, Menendez P, Bueno C. Lopez-Millan B, et al. Among authors: menendez p. Blood. 2024 Nov 7;144(19):2002-2017. doi: 10.1182/blood.2023022050. Blood. 2024. PMID: 39093982
NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid-lymphoid representation with limited graft-versus-host disease.
Panisello C, Aschero R, Martinez-Moreno A, Roca Ho H, Falgas A, González-Navarro EA, Carabelli J, Pradenas E, Lázaro-Díez M, Prado JG, Blanco J, Carrillo J, Juan M, Carcaboso ÁM, Bueno C, Menendez P. Panisello C, et al. Among authors: menendez p. J Immunother Cancer. 2024 Oct 7;12(10):e009198. doi: 10.1136/jitc-2024-009198. J Immunother Cancer. 2024. PMID: 39379097 Free PMC article.
372 results