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Gut bacteria convert glucocorticoids into progestins in the presence of hydrogen gas.
McCurry MD, D'Agostino GD, Walsh JT, Bisanz JE, Zalosnik I, Dong X, Morris DJ, Korzenik JR, Edlow AG, Balskus EP, Turnbaugh PJ, Huh JR, Devlin AS. McCurry MD, et al. Among authors: turnbaugh pj. Cell. 2024 Jun 6;187(12):2952-2968.e13. doi: 10.1016/j.cell.2024.05.005. Epub 2024 May 24. Cell. 2024. PMID: 38795705
Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors.
Kyaw TS, Zhang C, Sandy M, Trepka K, Zhang S, Ramirez Hernandez LA, Ramirez L, Goh JJN, Yu K, Dimassa V, Bess EN, Brockert JG, Dumlao DS, Bisanz JE, Turnbaugh PJ. Kyaw TS, et al. Among authors: turnbaugh pj. iScience. 2024 May 27;27(6):110122. doi: 10.1016/j.isci.2024.110122. eCollection 2024 Jun 21. iScience. 2024. PMID: 38947502 Free PMC article.
A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity.
Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. Alexander M, et al. Among authors: turnbaugh pj. Cell Rep. 2024 Oct 18:114891. doi: 10.1016/j.celrep.2024.114891. Online ahead of print. Cell Rep. 2024. PMID: 39500329 Free article.
Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice.
Tian Y, Rimal B, Bisanz JE, Gui W, Wolfe TM, Koo I, Murray IA, Nettleford SK, Yokoyama S, Dong F, Koshkin S, Prabhu KS, Turnbaugh PJ, Walk ST, Perdew GH, Patterson AD. Tian Y, et al. Among authors: turnbaugh pj. Environ Health Perspect. 2024 Aug;132(8):87005. doi: 10.1289/EHP13356. Epub 2024 Aug 14. Environ Health Perspect. 2024. PMID: 39140734 Free PMC article.
Rationale and protocol for a safety, tolerability and feasibility randomized, parallel group, double-blind, placebo-controlled, pilot study of a novel ketone ester targeting frailty via immunometabolic geroscience mechanisms.
Stubbs BJ, Alvarez-Azanedo G, Peralta S, Roa-Diaz S, Gray W, Alexander L, Silverman-Martin W, Garcia T, Blonquist TM, Upadhyay V, Turnbaugh PJ, Johnson JB, Newman JC. Stubbs BJ, et al. Among authors: turnbaugh pj. medRxiv [Preprint]. 2023 Oct 26:2023.10.25.23297571. doi: 10.1101/2023.10.25.23297571. medRxiv. 2023. Update in: PLoS One. 2024 Sep 18;19(9):e0307951. doi: 10.1371/journal.pone.0307951. PMID: 37961234 Free PMC article. Updated. Preprint.
138 results