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Page 1
Pantothenate kinase 4 controls skeletal muscle substrate metabolism.
Miranda-Cervantes A, Fritzen AM, Raun SH, Hodek O, Møller LLV, Johann K, Deisen L, Gregorevic P, Gudiksen A, Artati A, Adamski J, Andersen NR, Sigvardsen CM, Carl CS, Voldstedlund CT, Kjøbsted R, Hauck SM, Schjerling P, Jensen TE, Cebrian-Serrano A, Jähnert M, Gottmann P, Burtscher I, Lickert H, Pilegaard H, Schürmann A, Tschöp MH, Moritz T, Müller TD, Sylow L, Kiens B, Richter EA, Kleinert M. Miranda-Cervantes A, et al. Among authors: sigvardsen cm. Nat Commun. 2025 Jan 2;16(1):345. doi: 10.1038/s41467-024-55036-w. Nat Commun. 2025. PMID: 39746949 Free PMC article.
GDF15 is still a mystery hormone.
Sigvardsen CM, Richter MM, Engelbeen S, Kleinert M, Richter EA. Sigvardsen CM, et al. Trends Endocrinol Metab. 2024 Oct 29:S1043-2760(24)00254-6. doi: 10.1016/j.tem.2024.09.002. Online ahead of print. Trends Endocrinol Metab. 2024. PMID: 39472228 Review.
GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism.
Sjøberg KA, Sigvardsen CM, Alvarado-Diaz A, Andersen NR, Larance M, Seeley RJ, Schjerling P, Knudsen JG, Katzilieris-Petras G, Clemmensen C, Jørgensen SB, De Bock K, Richter EA. Sjøberg KA, et al. Among authors: sigvardsen cm. Cell Metab. 2023 Aug 8;35(8):1327-1340.e5. doi: 10.1016/j.cmet.2023.06.016. Epub 2023 Jul 19. Cell Metab. 2023. PMID: 37473755 Free article.