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Genome-wide screen of Mycobacterium tuberculosis- infected macrophages identified the GID/CTLH complex as a determinant of intracellular bacterial growth.
Simwela NV, Johnston L, Pavinski Bitar P, Jaecklein E, Altier C, Sassetti CM, Russell DG. Simwela NV, et al. bioRxiv [Preprint]. 2024 May 8:2024.05.06.592714. doi: 10.1101/2024.05.06.592714. bioRxiv. 2024. Update in: Nat Commun. 2024 Oct 29;15(1):9322. doi: 10.1038/s41467-024-53637-z PMID: 38766174 Free PMC article. Updated. Preprint.
Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
Zhan W, Li D, Subramanyaswamy SB, Liu YJ, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H, Sherman J, Qin J, Herring M, Simwela NV, Waters AP, Sukenick G, Cui L, Rodriguez A, Deng H, Nathan CF, Kirkman LA, Lin G. Zhan W, et al. Among authors: simwela nv. Cell Chem Biol. 2023 May 18;30(5):457-469.e11. doi: 10.1016/j.chembiol.2023.04.006. Epub 2023 May 5. Cell Chem Biol. 2023. PMID: 37148884 Free PMC article.
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