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Page 1
Protumoral lipid droplet-loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted.
Governa V, de Oliveira KG, Bång-Rudenstam A, Offer S, Cerezo-Magaña M, Li J, Beyer S, Johansson MC, Månsson AS, Edvardsson C, Durmo F, Gustafsson E, Boukredine A, Jeannot P, Schmidt K, Gezelius E, Menard JA, Garza R, Jakobsson J, de Neergaard T, Sundgren PC, Tiihonen AM, Haapasalo H, Rautajoki KJ, Nordenfelt P, Darabi A, Forsberg-Nilsson K, Pietras A, Talbot H, Bengzon J, Belting M. Governa V, et al. Among authors: johansson mc. Sci Transl Med. 2024 Oct 30;16(771):eadk1168. doi: 10.1126/scitranslmed.adk1168. Epub 2024 Oct 30. Sci Transl Med. 2024. PMID: 39475570
Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration.
Offer S, Menard JA, Pérez JE, de Oliveira KG, Indira Chandran V, Johansson MC, Bång-Rudenstam A, Siesjö P, Ebbesson A, Hedenfalk I, Sundgren PC, Darabi A, Belting M. Offer S, et al. Among authors: johansson mc. J Exp Clin Cancer Res. 2019 Jun 7;38(1):241. doi: 10.1186/s13046-019-1228-6. J Exp Clin Cancer Res. 2019. PMID: 31174567 Free PMC article.
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche.
de Oliveira KG, Bång-Rudenstam A, Beyer S, Boukredine A, Talbot H, Governa V, Johansson MC, Månsson AS, Forsberg-Nilsson K, Bengzon J, Malmström J, Welinder C, Belting M. de Oliveira KG, et al. Among authors: johansson mc. Acta Neuropathol Commun. 2024 Feb 27;12(1):35. doi: 10.1186/s40478-024-01740-z. Acta Neuropathol Commun. 2024. PMID: 38414005 Free PMC article.
Ultrasensitive Immunoprofiling of Plasma Extracellular Vesicles Identifies Syndecan-1 as a Potential Tool for Minimally Invasive Diagnosis of Glioma.
Indira Chandran V, Welinder C, Månsson AS, Offer S, Freyhult E, Pernemalm M, Lund SM, Pedersen S, Lehtiö J, Marko-Varga G, Johansson MC, Englund E, Sundgren PC, Belting M. Indira Chandran V, et al. Among authors: johansson mc. Clin Cancer Res. 2019 May 15;25(10):3115-3127. doi: 10.1158/1078-0432.CCR-18-2946. Epub 2019 Jan 24. Clin Cancer Res. 2019. PMID: 30679164
Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics.
Indira Chandran V, Welinder C, Gonçalves de Oliveira K, Cerezo-Magaña M, Månsson AS, Johansson MC, Marko-Varga G, Belting M. Indira Chandran V, et al. Among authors: johansson mc. J Neurooncol. 2019 Sep;144(3):477-488. doi: 10.1007/s11060-019-03262-4. Epub 2019 Aug 14. J Neurooncol. 2019. PMID: 31414377 Free PMC article.
Landscape of surfaceome and endocytome in human glioma is divergent and depends on cellular spatial organization.
Governa V, Talbot H, Gonçalves de Oliveira K, Cerezo-Magaña M, Bång-Rudenstam A, Johansson MC, Månsson AS, Forsberg-Nilsson K, Marko-Varga G, Enríquez Pérez J, Darabi A, Malmström J, Bengzon J, Welinder C, Belting M. Governa V, et al. Among authors: johansson mc. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2114456119. doi: 10.1073/pnas.2114456119. Proc Natl Acad Sci U S A. 2022. PMID: 35217608 Free PMC article.
Metastasis Stimulation by Hypoxia and Acidosis-Induced Extracellular Lipid Uptake Is Mediated by Proteoglycan-Dependent Endocytosis.
Menard JA, Christianson HC, Kucharzewska P, Bourseau-Guilmain E, Svensson KJ, Lindqvist E, Indira Chandran V, Kjellén L, Welinder C, Bengzon J, Johansson MC, Belting M. Menard JA, et al. Among authors: johansson mc. Cancer Res. 2016 Aug 15;76(16):4828-40. doi: 10.1158/0008-5472.CAN-15-2831. Epub 2016 May 19. Cancer Res. 2016. PMID: 27199348
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells.
Svensson KJ, Kucharzewska P, Christianson HC, Sköld S, Löfstedt T, Johansson MC, Mörgelin M, Bengzon J, Ruf W, Belting M. Svensson KJ, et al. Among authors: johansson mc. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13147-52. doi: 10.1073/pnas.1104261108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788507 Free PMC article.
ScFv antibody-induced translocation of cell-surface heparan sulfate proteoglycan to endocytic vesicles: evidence for heparan sulfate epitope specificity and role of both syndecan and glypican.
Wittrup A, Zhang SH, ten Dam GB, van Kuppevelt TH, Bengtson P, Johansson M, Welch J, Mörgelin M, Belting M. Wittrup A, et al. J Biol Chem. 2009 Nov 20;284(47):32959-67. doi: 10.1074/jbc.M109.036129. Epub 2009 Sep 25. J Biol Chem. 2009. PMID: 19783663 Free PMC article.
50 results