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Protumoral lipid droplet-loaded macrophages are enriched in human glioblastoma and can be therapeutically targeted.
Governa V, de Oliveira KG, Bång-Rudenstam A, Offer S, Cerezo-Magaña M, Li J, Beyer S, Johansson MC, Månsson AS, Edvardsson C, Durmo F, Gustafsson E, Boukredine A, Jeannot P, Schmidt K, Gezelius E, Menard JA, Garza R, Jakobsson J, de Neergaard T, Sundgren PC, Tiihonen AM, Haapasalo H, Rautajoki KJ, Nordenfelt P, Darabi A, Forsberg-Nilsson K, Pietras A, Talbot H, Bengzon J, Belting M. Governa V, et al. Among authors: pietras a. Sci Transl Med. 2024 Oct 30;16(771):eadk1168. doi: 10.1126/scitranslmed.adk1168. Epub 2024 Oct 30. Sci Transl Med. 2024. PMID: 39475570
The Irradiated Brain Microenvironment Supports Glioma Stemness and Survival via Astrocyte-Derived Transglutaminase 2.
Berg TJ, Marques C, Pantazopoulou V, Johansson E, von Stedingk K, Lindgren D, Jeannot P, Pietras EJ, Bergström T, Swartling FJ, Governa V, Bengzon J, Belting M, Axelson H, Squatrito M, Pietras A. Berg TJ, et al. Among authors: pietras ej, pietras a. Cancer Res. 2021 Apr 15;81(8):2101-2115. doi: 10.1158/0008-5472.CAN-20-1785. Epub 2021 Jan 22. Cancer Res. 2021. PMID: 33483373
Niche-derived soluble DLK1 promotes glioma growth.
Grassi ES, Jeannot P, Pantazopoulou V, Berg TJ, Pietras A. Grassi ES, et al. Among authors: pietras a. Neoplasia. 2020 Dec;22(12):689-701. doi: 10.1016/j.neo.2020.10.005. Epub 2020 Oct 23. Neoplasia. 2020. PMID: 33142235 Free PMC article.
Complement factor H is an ICOS ligand modulating Tregs in the glioma microenvironment.
Smolag KI, Olszowka J, Rosberg R, Johansson E, Marinko E, Leandersson K, O'Connell DJ, Governa V, Tuysuz EC, Belting M, Pietras A, Martin M, Blom AM. Smolag KI, et al. Among authors: pietras a. Cancer Immunol Res. 2024 Oct 10. doi: 10.1158/2326-6066.CIR-23-1092. Online ahead of print. Cancer Immunol Res. 2024. PMID: 39378431
57 results