George RF - Search Results

1

Discovery of pyrazole-based analogs as CDK2 inhibitors with apoptotic-inducing activity: design, synthesis and molecular dynamics study.

Ali GME, Ewida MA, Elmetwali AM, Ewida HA, George RF, Mahmoud WR, Ismail NSM, Ahmed MS, Georgey HH. Ali GME, et al. Among authors: george rf. RSC Adv. 2024 Oct 29;14(47):34537-34555. doi: 10.1039/d4ra06500j. eCollection 2024 Oct 29. RSC Adv. 2024. PMID: 39479486 Free PMC article.

2

Design, synthesis, in silico docking, ADMET and anticancer evaluations of thiazolidine-2,4-diones bearing heterocyclic rings as dual VEGFR-2/EGFR^T790M tyrosine kinase inhibitors.

Aziz NAAM, George RF, El-Adl K, Mahmoud WR. Aziz NAAM, et al. Among authors: george rf. RSC Adv. 2022 Apr 27;12(20):12913-12931. doi: 10.1039/d2ra01119k. eCollection 2022 Apr 22. RSC Adv. 2022. PMID: 35496328 Free PMC article.

3

Construction of some cytotoxic agents with aurone and furoaurone scaffolds.

Hassan GS, Georgey HH, George RF, Mohammed ER. Hassan GS, et al. Among authors: george rf. Future Med Chem. 2018 Jan;10(1):27-52. doi: 10.4155/fmc-2017-0147. Epub 2017 Dec 13. Future Med Chem. 2018. PMID: 29235893

4

Identification of some benzoxazepines as anticancer agents inducing cancer cell apoptosis.

Rashad MS, Georgey HH, George RF, Abdel-Gawad NM. Rashad MS, et al. Among authors: george rf. Future Med Chem. 2018 Jul 1;10(14):1649-1664. doi: 10.4155/fmc-2018-0068. Epub 2018 Jun 29. Future Med Chem. 2018. PMID: 29957068

5

Mechanistic selectivity investigation and 2D-QSAR study of some new antiproliferative pyrazoles and pyrazolopyridines as potential CDK2 inhibitors.

Hassan GS, Georgey HH, Mohammed EZ, George RF, Mahmoud WR, Omar FA. Hassan GS, et al. Among authors: george rf. Eur J Med Chem. 2021 Jun 5;218:113389. doi: 10.1016/j.ejmech.2021.113389. Epub 2021 Mar 18. Eur J Med Chem. 2021. PMID: 33784602

6

Nanomolar potency of imidazo[2,1-b]thiazole analogs as indoleamine 2,3-dioxygenase inhibitors.

Ewida MA, Ewida HA, Ahmed MS, Allam HA, ElBagary RI, George RF, Georgey HH, El-Subbagh HI. Ewida MA, et al. Among authors: george rf. Arch Pharm (Weinheim). 2021 Nov;354(11):e2100202. doi: 10.1002/ardp.202100202. Epub 2021 Jul 27. Arch Pharm (Weinheim). 2021. PMID: 34313342

7

3-Methyl-imidazo[2,1-b]thiazole derivatives as a new class of antifolates: Synthesis, in vitro/in vivo bio-evaluation and molecular modeling simulations.

Ewida MA, Ewida HA, Ahmed MS, Allam HA, ElBagary RI, George RF, Georgey HH, El-Subbagh HI. Ewida MA, et al. Among authors: george rf. Bioorg Chem. 2021 Oct;115:105205. doi: 10.1016/j.bioorg.2021.105205. Epub 2021 Jul 24. Bioorg Chem. 2021. PMID: 34329992

8

Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs).

Mohammed EZ, Mahmoud WR, George RF, Hassan GS, Omar FA, Georgey HH. Mohammed EZ, et al. Among authors: george rf. Bioorg Chem. 2021 Nov;116:105347. doi: 10.1016/j.bioorg.2021.105347. Epub 2021 Sep 11. Bioorg Chem. 2021. PMID: 34555628

9

Bacterial virulence factors: a target for heterocyclic compounds to combat bacterial resistance.

Abd El-Aleam RH, George RF, Georgey HH, Abdel-Rahman HM. Abd El-Aleam RH, et al. Among authors: george rf. RSC Adv. 2021 Nov 19;11(58):36459-36482. doi: 10.1039/d1ra06238g. eCollection 2021 Nov 10. RSC Adv. 2021. PMID: 35494393 Free PMC article. Review.

10

New quinazolinone-based derivatives as DHFR/EGFR-TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity.

El-Gazzar YI, Ghaiad HR, El Kerdawy AM, George RF, Georgey HH, Youssef KM, El-Subbagh HI. El-Gazzar YI, et al. Among authors: george rf. Arch Pharm (Weinheim). 2023 Jan;356(1):e2200417. doi: 10.1002/ardp.202200417. Epub 2022 Oct 18. Arch Pharm (Weinheim). 2023. PMID: 36257809

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