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The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth.
Edman S, Jones Iii RG, Jannig PR, Fernandez-Gonzalo R, Norrbom J, Thomas NT, Khadgi S, Koopmans PJ, Morena F, Chambers TL, Peterson CS, Scott LN, Greene NP, Figueiredo VC, Fry CS, Zhengye L, Lanner JT, Wen Y, Alkner B, Murach KA, von Walden F. Edman S, et al. Among authors: wen y. EMBO Rep. 2024 Dec;25(12):5810-5837. doi: 10.1038/s44319-024-00299-z. Epub 2024 Oct 31. EMBO Rep. 2024. PMID: 39482487 Free PMC article.
Genetic and epigenetic regulation of skeletal muscle ribosome biogenesis with exercise.
Figueiredo VC, Wen Y, Alkner B, Fernandez-Gonzalo R, Norrbom J, Vechetti IJ Jr, Valentino T, Mobley CB, Zentner GE, Peterson CA, McCarthy JJ, Murach KA, von Walden F. Figueiredo VC, et al. Among authors: wen y. J Physiol. 2021 Jul;599(13):3363-3384. doi: 10.1113/JP281244. Epub 2021 Jun 3. J Physiol. 2021. PMID: 33913170 Free article.
Senolytic treatment rescues blunted muscle hypertrophy in old mice.
Dungan CM, Figueiredo VC, Wen Y, VonLehmden GL, Zdunek CJ, Thomas NT, Mobley CB, Murach KA, Brightwell CR, Long DE, Fry CS, Kern PA, McCarthy JJ, Peterson CA. Dungan CM, et al. Among authors: wen y. Geroscience. 2022 Aug;44(4):1925-1940. doi: 10.1007/s11357-022-00542-2. Epub 2022 Mar 24. Geroscience. 2022. PMID: 35325353 Free PMC article.
Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks.
Murach KA, Liu Z, Jude B, Figueiredo VC, Wen Y, Khadgi S, Lim S, Morena da Silva F, Greene NP, Lanner JT, McCarthy JJ, Vechetti IJ, von Walden F. Murach KA, et al. Among authors: wen y. J Biol Chem. 2022 Nov;298(11):102515. doi: 10.1016/j.jbc.2022.102515. Epub 2022 Sep 21. J Biol Chem. 2022. PMID: 36150502 Free PMC article.
A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.
Jones RG 3rd, Dimet-Wiley A, Haghani A, da Silva FM, Brightwell CR, Lim S, Khadgi S, Wen Y, Dungan CM, Brooke RT, Greene NP, Peterson CA, McCarthy JJ, Horvath S, Watowich SJ, Fry CS, Murach KA. Jones RG 3rd, et al. Among authors: wen y. J Physiol. 2023 Feb;601(4):763-782. doi: 10.1113/JP283836. Epub 2023 Jan 24. J Physiol. 2023. PMID: 36533424 Free PMC article.
Coordinated Regulation of Myonuclear DNA Methylation, mRNA, and miRNA Levels Associates With the Metabolic Response to Rapid Synergist Ablation-Induced Skeletal Muscle Hypertrophy in Female Mice.
Ismaeel A, Thomas NT, McCashland M, Vechetti IJ, Edman S, Lanner JT, Figueiredo VC, Fry CS, McCarthy JJ, Wen Y, Murach KA, von Walden F. Ismaeel A, et al. Among authors: wen y. Function (Oxf). 2023 Nov 6;5(1):zqad062. doi: 10.1093/function/zqad062. eCollection 2024. Function (Oxf). 2023. PMID: 38020067 Free PMC article.
The rRNA epitranscriptome and myonuclear SNORD landscape in skeletal muscle fibers contributes to ribosome heterogeneity and is altered by a hypertrophic stimulus.
Cui M, Jannig P, Halladjian M, Figueiredo VC, Wen Y, Vechetti IJ, Krogh N, Jude B, Edman S, Lanner J, McCarthy J, Murach KA, Sejersen T, Nielsen H, von Walden F. Cui M, et al. Among authors: wen y. Am J Physiol Cell Physiol. 2024 Sep 1;327(3):C516-C524. doi: 10.1152/ajpcell.00301.2024. Epub 2024 Jun 24. Am J Physiol Cell Physiol. 2024. PMID: 38912733 Free PMC article.
9,629 results