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Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF).
Gibb AA, LaPenna K, Gaspar RB, Latchman NR, Tan Y, Choya-Foces C, Doiron JE, Li Z, Xia H, Lazaropoulos MP, Conwell M, Sharp TE 3rd, Goodchild TT, Lefer DJ, Elrod JW. Gibb AA, et al. Among authors: tan y. bioRxiv [Preprint]. 2024 Oct 25:2024.10.25.619450. doi: 10.1101/2024.10.25.619450. bioRxiv. 2024. PMID: 39484400 Free PMC article. Preprint.
Netrin G1 Ligand is a new stromal immunomodulator that promotes pancreatic cancer.
Vendramini-Costa DB, Francescone R, Franco-Barraza J, Luong T, Graves M, de Aquino AM, Steele N, Gardiner JC, Dos Santos SAA, Ogier C, Malloy E, Borghaei L, Martinez E, Zhigarev DI, Tan Y, Lee H, Zhou Y, Cai KQ, Klein-Szanto AJ, Wang H, Andrake M, Dunbrack RL, Campbell K, Cukierman E. Vendramini-Costa DB, et al. Among authors: tan y. bioRxiv [Preprint]. 2024 May 18:2024.05.15.594354. doi: 10.1101/2024.05.15.594354. bioRxiv. 2024. PMID: 38798370 Free PMC article. Preprint.
Autophagy contributes to homeostasis in esophageal epithelium where high autophagic vesicle content marks basal cells with limited proliferation and enhanced self-renewal potential.
Klochkova A, Karami AL, Fuller AD, Parham LR, Panchani SR, Natarajan S, Jackson JL, Mu A, Tan Y, Cai KQ, Klein-Szanto AJ, Muir AB, Tétreault MP, Hamilton KE, Whelan KA. Klochkova A, et al. Among authors: tan y. bioRxiv [Preprint]. 2023 Sep 22:2023.09.20.558614. doi: 10.1101/2023.09.20.558614. bioRxiv. 2023. Update in: Cell Mol Gastroenterol Hepatol. 2024;18(1):15-40. doi: 10.1016/j.jcmgh.2024.02.018 PMID: 37781581 Free PMC article. Updated. Preprint.
Thyroid Hormone Suppresses Medulloblastoma Progression Through Promoting Terminal Differentiation of Tumor Cells.
Yang Y, Valdés-Rives SA, Liu Q, Li Y, Tan J, Tan Y, Koch CA, Rong Y, Houser SR, Wei S, Cai KQ, Cheng SY, Curran T, Wechsler-Reya R, Yang ZJ. Yang Y, et al. Among authors: tan y, tan j. bioRxiv [Preprint]. 2024 Feb 15:2024.02.13.580111. doi: 10.1101/2024.02.13.580111. bioRxiv. 2024. Update in: Cancer Cell. 2024 Aug 12;42(8):1434-1449.e5. doi: 10.1016/j.ccell.2024.07.008 PMID: 38405864 Free PMC article. Updated. Preprint.
Inhibition of DKK-1 by WAY262611 Inhibits Osteosarcoma Metastasis.
Tal A, Gunawardana-Zeigler S, Peng D, Tan Y, Perez NM, Offenbacher R, Kastner L, Ciero P, Randolph ME, Gong Y, Deng HW, Cahan P, Loeb DM. Tal A, et al. Among authors: tan y. bioRxiv [Preprint]. 2024 Dec 11:2024.12.10.627181. doi: 10.1101/2024.12.10.627181. bioRxiv. 2024. PMID: 39713389 Free PMC article. Preprint.
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