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The cyclin-G associated kinase (GAK) is a novel mitotic kinase and therapeutic target in diffuse large B-cell lymphoma.
Lightfuss OB, Kumar P, Li L, Shastri T, Newsam AD, Manara P, Alaoui AY, Parets DEH, Younes PA, Chahar D, Arumov A, Coughlin CA, Williams IP, Fattakhov N, Martinez AB, Landgren O, Schurer SC, Lemmon V, Maura F, Bilbao D, Feng Y, Al-Ali H, Schatz JH. Lightfuss OB, et al. Among authors: newsam ad. bioRxiv [Preprint]. 2024 Oct 26:2024.10.21.619489. doi: 10.1101/2024.10.21.619489. bioRxiv. 2024. PMID: 39484514 Free PMC article. Preprint.
NRF2 translation block by inhibition of cap-dependent initiation sensitizes lymphoma cells to ferroptosis and CAR-T immunotherapy.
Manara P, Newsam AD, Saralamma VV, Russo MV, Martinez AB, Fattakhov N, Cunningham TA, Alaoui AY, Chahar D, Carbone AM, Lightfuss OB, Barroso AM, Hoffman KS, Maura F, Bilbao D, Schatz JH. Manara P, et al. Among authors: newsam ad. bioRxiv [Preprint]. 2024 Sep 13:2024.09.09.612133. doi: 10.1101/2024.09.09.612133. bioRxiv. 2024. PMID: 39314323 Free PMC article. Preprint.