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Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME.
de Freitas JT, Thakur V, LaPorte KM, Thakur VS, Flores B, Caicedo V, Ajaegbu CGE, Ingrasci G, Lipman ZM, Zhang K, Qiu H, Malek TR, Bedogni B. de Freitas JT, et al. Among authors: laporte km. J Exp Clin Cancer Res. 2024 Nov 4;43(1):295. doi: 10.1186/s13046-024-03214-5. J Exp Clin Cancer Res. 2024. PMID: 39491031 Free PMC article.
Engineering IL-2 for immunotherapy of autoimmunity and cancer.
Hernandez R, Põder J, LaPorte KM, Malek TR. Hernandez R, et al. Among authors: laporte km. Nat Rev Immunol. 2022 Oct;22(10):614-628. doi: 10.1038/s41577-022-00680-w. Epub 2022 Feb 25. Nat Rev Immunol. 2022. PMID: 35217787 Review.
Morphine-induced intestinal microbial dysbiosis drives TLR-dependent IgA targeting of gram-positive bacteria and upregulation of CD11b and TLR2 on a sub-population of IgA+ B cells.
Vitari N, Singh S, Tao J, Truitt B, Kolli U, Jalodia R, LaPorte KM, Abu Y, Antoine D, Sharma U, Roy S. Vitari N, et al. Among authors: laporte km. Gut Microbes. 2024 Jan-Dec;16(1):2417729. doi: 10.1080/19490976.2024.2417729. Epub 2024 Oct 23. Gut Microbes. 2024. PMID: 39441178 Free PMC article.
Arts therapies promote wellness in elders.
Zeltzer BB, Stanley S, Melo L, LaPorte KM. Zeltzer BB, et al. Among authors: laporte km. Behav Healthc Tomorrow. 2003 Apr;12(2):7-12. Behav Healthc Tomorrow. 2003. PMID: 12698737 No abstract available.