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Residual microglia following short-term PLX5622 treatment in 5xFAD mice exhibit diminished NLRP3 inflammasome and mTOR signaling, and enhanced autophagy.
Kodali M, Madhu LN, Somayaji Y, Attaluri S, Huard C, Panda PK, Shankar G, Rao S, Shuai B, Gonzalez JJ, Oake C, Hering C, Babu RS, Kotian S, Shetty AK. Kodali M, et al. Among authors: madhu ln. Aging Cell. 2024 Nov 21:e14398. doi: 10.1111/acel.14398. Online ahead of print. Aging Cell. 2024. PMID: 39571180 Free article.
Extracellular vesicles from human-induced pluripotent stem cell-derived neural stem cells alleviate proinflammatory cascades within disease-associated microglia in Alzheimer's disease.
Madhu LN, Kodali M, Upadhya R, Rao S, Somayaji Y, Attaluri S, Shuai B, Kirmani M, Gupta S, Maness N, Rao X, Cai JJ, Shetty AK. Madhu LN, et al. J Extracell Vesicles. 2024 Nov;13(11):e12519. doi: 10.1002/jev2.12519. J Extracell Vesicles. 2024. PMID: 39499013 Free PMC article.
Residual Microglia Following Short-term PLX5622 Treatment in 5xFAD Mice Exhibit Diminished NLRP3 Inflammasome and mTOR Signaling, and Enhanced Autophagy.
Kodali M, Madhu LN, Somayaji Y, Attaluri S, Huard C, Panda PK, Shankar G, Rao S, Shuai B, Gonzalez JJ, Oake C, Hering C, Babu RS, Kotian S, Shetty AK. Kodali M, et al. Among authors: madhu ln. bioRxiv [Preprint]. 2024 Jul 16:2024.07.11.603157. doi: 10.1101/2024.07.11.603157. bioRxiv. 2024. Update in: Aging Cell. 2024 Nov 21:e14398. doi: 10.1111/acel.14398 PMID: 39071343 Free PMC article. Updated. Preprint.
Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus.
Ayyubova G, Kodali M, Upadhya R, Madhu LN, Attaluri S, Somayaji Y, Shuai B, Rao S, Shankar G, Shetty AK. Ayyubova G, et al. Among authors: madhu ln. J Neuroinflammation. 2023 Dec 12;20(1):297. doi: 10.1186/s12974-023-02971-y. J Neuroinflammation. 2023. PMID: 38087314 Free PMC article.
Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice.
Attaluri S, Jaimes Gonzalez J, Kirmani M, Vogel AD, Upadhya R, Kodali M, Madhu LN, Rao S, Shuai B, Babu RS, Huard C, Shetty AK. Attaluri S, et al. Among authors: madhu ln. Front Aging Neurosci. 2023 Jun 22;15:1200445. doi: 10.3389/fnagi.2023.1200445. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37424631 Free PMC article.
A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB signaling.
Kodali M, Madhu LN, Reger RL, Milutinovic B, Upadhya R, Attaluri S, Shuai B, Shankar G, Shetty AK. Kodali M, et al. Among authors: madhu ln. Front Mol Neurosci. 2023 May 22;16:1185883. doi: 10.3389/fnmol.2023.1185883. eCollection 2023. Front Mol Neurosci. 2023. PMID: 37284464 Free PMC article.
Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction.
Kodali M, Madhu LN, Reger RL, Milutinovic B, Upadhya R, Gonzalez JJ, Attaluri S, Shuai B, Gitai DLG, Rao S, Choi JM, Jung SY, Shetty AK. Kodali M, et al. Among authors: madhu ln. Brain Behav Immun. 2023 Feb;108:118-134. doi: 10.1016/j.bbi.2022.11.014. Epub 2022 Nov 24. Brain Behav Immun. 2023. PMID: 36427808 Free PMC article.
29 results