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Page 1
Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade.
Cruz Tleugabulova M, Melo SP, Wong A, Arlantico A, Liu M, Webster JD, Lau J, Lechner A, Corak B, Hodgins JJ, Garlapati VS, De Simone M, Korin B, Avraham S, Lund J, Jeet S, Reiss A, Bender H, Austin CD, Darmanis S, Modrusan Z, Brightbill H, Durinck S, Diamond MS, Schneider C, Shaw AS, Nitschké M. Cruz Tleugabulova M, et al. Among authors: darmanis s. Nat Commun. 2024 Nov 6;15(1):9575. doi: 10.1038/s41467-024-53700-9. Nat Commun. 2024. PMID: 39505846 Free PMC article.
A comprehensive analysis framework for evaluating commercial single-cell RNA sequencing technologies.
De Simone M, Hoover J, Lau J, Bennett HM, Wu B, Chen C, Menon H, Au-Yeung A, Lear S, Vaidya S, Shi M, Lund JM, Xavier-Magalhães A, Liang Y, Kurdoglu A, O'Gorman WE, Modrusan Z, Le D, Darmanis S. De Simone M, et al. Among authors: darmanis s. Nucleic Acids Res. 2024 Dec 16:gkae1186. doi: 10.1093/nar/gkae1186. Online ahead of print. Nucleic Acids Res. 2024. PMID: 39675380
Coordinated wound responses in a regenerative animal-algal holobiont.
Nanes Sarfati D, Xue Y, Song ES, Byrne A, Le D, Darmanis S, Quake SR, Burlacot A, Sikes J, Wang B. Nanes Sarfati D, et al. Among authors: darmanis s. Nat Commun. 2024 May 13;15(1):4032. doi: 10.1038/s41467-024-48366-2. Nat Commun. 2024. PMID: 38740753 Free PMC article.
Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris.
Tabula Muris Consortium; Overall coordination; Logistical coordination; Organ collection and processing; Library preparation and sequencing; Computational data analysis; Cell type annotation; Writing group; Supplemental text writing group; Principal investigators. Tabula Muris Consortium, et al. Nature. 2018 Oct;562(7727):367-372. doi: 10.1038/s41586-018-0590-4. Epub 2018 Oct 3. Nature. 2018. PMID: 30283141 Free PMC article.
Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.
Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z. Winkler J, et al. Among authors: darmanis s. J Clin Invest. 2024 Sep 3;134(17):e164227. doi: 10.1172/JCI164227. J Clin Invest. 2024. PMID: 39225101 Free PMC article.
Overloading And unpacKing (OAK) - droplet-based combinatorial indexing for ultra-high throughput single-cell multiomic profiling.
Wu B, Bennett HM, Ye X, Sridhar A, Eidenschenk C, Everett C, Nazarova EV, Chen HH, Kim IK, Deangelis M, Owen LA, Chen C, Lau J, Shi M, Lund JM, Xavier-Magalhães A, Patel N, Liang Y, Modrusan Z, Darmanis S. Wu B, et al. Among authors: darmanis s. Nat Commun. 2024 Oct 23;15(1):9146. doi: 10.1038/s41467-024-53227-z. Nat Commun. 2024. PMID: 39443484 Free PMC article.
IL-4-induced SOX9 confers lineage plasticity to aged adult lung stem cells.
Cai XT, Jia M, Heigl T, Shamir ER, Wong AK, Hall BM, Arlantico A, Hung J, Menon HG, Darmanis S, Brightbill HD, Garfield DA, Rock JR. Cai XT, et al. Among authors: darmanis s. Cell Rep. 2024 Aug 27;43(8):114569. doi: 10.1016/j.celrep.2024.114569. Epub 2024 Jul 31. Cell Rep. 2024. PMID: 39088319 Free article.
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, Krummel MF, Erle DJ, Kangelaris K, Sarma A, Lyon Z, Calfee CS, Woodruff PG, Ghale R, Mick E, Byrne A, Zha BS, Langelier C, Hendrickson CM, van der Wijst MGP, Hartoularos GC, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Ye CJ; UCSF COMET Consortium; Ramalingam T, McBride JM, Cai F, Teterina A, Bao M, Tsai L, Rosas IO, Regev A, Kapadia SB, Bauer RN, Rosenberger CM. Hackney JA, et al. iScience. 2023 Sep 1;26(10):107813. doi: 10.1016/j.isci.2023.107813. eCollection 2023 Oct 20. iScience. 2023. PMID: 37810211 Free PMC article.
71 results