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Inhibiting ADAM17 enhances the efficacy of olaparib in ovarian cancer spheroids.
Rogmans C, Dittrich J, Hamm E, Weimer JP, Holthaus D, Arnold N, Flörkemeier I, Maass N, Jansen P, Dempfle A, Bauerschlag DO, Hedemann N. Rogmans C, et al. Among authors: arnold n. Sci Rep. 2024 Nov 6;14(1):26926. doi: 10.1038/s41598-024-78442-y. Sci Rep. 2024. PMID: 39506058 Free PMC article.
Chemotherapy-induced release of ADAM17 bearing EV as a potential resistance mechanism in ovarian cancer.
Hugendieck G, Lettau M, Andreas S, Neumann S, Reinhardt N, Arnold P, Theilig F, Bastian L, Rogmans C, Weimer JP, Flörkemeier I, Wesch D, Arnold N, Maass N, Janssen O, Bauerschlag D, Hedemann N. Hugendieck G, et al. Among authors: arnold n, arnold p. J Extracell Vesicles. 2023 Jul;12(7):e12338. doi: 10.1002/jev2.12338. J Extracell Vesicles. 2023. PMID: 37408115 Free PMC article.
Multicellular ovarian cancer spheroids: novel 3D model to mimic tumour complexity.
Flörkemeier I, Antons LK, Weimer JP, Hedemann N, Rogmans C, Krüger S, Scherließ R, Dempfle A, Arnold N, Maass N, Bauerschlag DO. Flörkemeier I, et al. Among authors: arnold n. Sci Rep. 2024 Oct 9;14(1):23526. doi: 10.1038/s41598-024-73680-6. Sci Rep. 2024. PMID: 39384844 Free PMC article.
Limitations in next-generation sequencing-based genotyping of breast cancer polygenic risk score loci.
Baumann A, Ruckert C, Meier C, Hutschenreiter T, Remy R, Schnur B, Döbel M, Fankep RCN, Skowronek D, Kutz O, Arnold N, Katzke AL, Forster M, Kobiela AL, Thiedig K, Zimmer A, Ritter J, Weber BHF, Honisch E, Hackmann K; Bioinformatics Working Group of the German Consortium for Hereditary Breast & Ovarian Cancer; Schmidt G, Sturm M, Ernst C. Baumann A, et al. Among authors: arnold n. Eur J Hum Genet. 2024 Aug;32(8):987-997. doi: 10.1038/s41431-024-01647-2. Epub 2024 Jun 21. Eur J Hum Genet. 2024. PMID: 38907004 Free PMC article.
A critical spotlight on the paradigms of FFPE-DNA sequencing.
Steiert TA, Parra G, Gut M, Arnold N, Trotta JR, Tonda R, Moussy A, Gerber Z, Abuja PM, Zatloukal K, Röcken C, Folseraas T, Grimsrud MM, Vogel A, Goeppert B, Roessler S, Hinz S, Schafmayer C, Rosenstiel P, Deleuze JF, Gut IG, Franke A, Forster M. Steiert TA, et al. Among authors: arnold n. Nucleic Acids Res. 2023 Aug 11;51(14):7143-7162. doi: 10.1093/nar/gkad519. Nucleic Acids Res. 2023. PMID: 37351572 Free PMC article. Review.
The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells.
Issitt T, Toe QK, Pedersen SL, Shackshaft T, Ghazaly MM, West L, Arnold ND, Mahomed A, Kagugube GW, Ramakrishnan L, Lawrie A, Quinlan GJ, Wort SJ. Issitt T, et al. Among authors: arnold nd. Pulm Circ. 2024 Dec 18;14(4):e70006. doi: 10.1002/pul2.70006. eCollection 2024 Oct. Pulm Circ. 2024. PMID: 39697901 Free PMC article.
Childhood, adolescent and young adulthood cancer risk in BRCA1 or BRCA2 pathogenic variant carriers.
Li S, Madanat-Harjuoja L, Leslie G, Barnes DR, Bolla MK, Dennis J, Parsons MT, Apostolou P, Arnold N, Bosse K, On Behalf Of Embrace Collaborators ACA, Cook J, Engel C, Evans DG, Fostira F, Frone MN, Gehrig A, Greene MH, Hackmann K, Hahnen E, Harbeck N, Hauke J, Hentschel J, Horvath J, Izatt L, Kiechle M, Konstantopoulou I, Lalloo F, Yie JNY, Niederacher D, Ritter J, Santamariña M, Schmutzler RK, Searle C, Sutter C, Tischkowitz M, Tripathi V, Vega A, Wallaschek H, Wang-Gohrke S, Wappenschmidt B, Weber BHF, Yannoukakos D, Zhao E, Easton DF, Antoniou AC, Chenevix-Trench G, Rebbeck TR, Diller LR. Li S, et al. Among authors: arnold n. J Natl Cancer Inst. 2024 Nov 25:djae306. doi: 10.1093/jnci/djae306. Online ahead of print. J Natl Cancer Inst. 2024. PMID: 39585318
586 results