Xie HG - Search Results

1

Clopidogrel ameliorates high-fat diet-induced hepatic steatosis in mice through activation of the AMPK signaling pathway and beyond.

Tai T, Shao YY, Zheng YQ, Jiang LP, Han HR, Yin N, Li HD, Ji JZ, Mi QY, Yang L, Feng L, Duan FY, Xie HG. Tai T, et al. Among authors: xie hg. Front Pharmacol. 2024 Oct 23;15:1496639. doi: 10.3389/fphar.2024.1496639. eCollection 2024. Front Pharmacol. 2024. PMID: 39508046 Free PMC article.

2

P-glycoprotein deficiency enhances metabolic activation of and platelet response to clopidogrel through marked up-regulation of Cyp3a11 in mice: Direct evidence for the interplay between P-glycoprotein and Cyp3a.

Ji JZ, Li YF, Jiang LP, Tai T, Ge PX, Mi QY, Zhu T, Xie HG. Ji JZ, et al. Among authors: xie hg. Biochem Pharmacol. 2021 Jan;183:114313. doi: 10.1016/j.bcp.2020.114313. Epub 2020 Nov 1. Biochem Pharmacol. 2021. PMID: 33137324

3

Is platelet responsiveness to clopidogrel attenuated in overweight or obese patients and why? A reverse translational study in mice.

Jiang LP, Ji JZ, Ge PX, Zhu T, Mi QY, Tai T, Li YF, Xie HG. Jiang LP, et al. Among authors: xie hg. Br J Pharmacol. 2022 Jan;179(1):46-64. doi: 10.1111/bph.15667. Epub 2021 Oct 29. Br J Pharmacol. 2022. PMID: 34415054 Free article.

4

Sex differences in the metabolic activation of and platelet response to vicagrel in mice: Androgen as a key player.

Jiang LP, Fu M, Yin N, Jia YM, Duan FY, Feng L, Yang L, Han HR, Wang J, Zhu T, Ji JZ, Tai T, Li XM, Zheng ZD, Ding PJ, Sun YL, Mi QY, Xie HG. Jiang LP, et al. Among authors: xie hg. Biochem Pharmacol. 2024 Dec;230(Pt 1):116564. doi: 10.1016/j.bcp.2024.116564. Epub 2024 Oct 2. Biochem Pharmacol. 2024. PMID: 39366431

5

The molecular mechanism underlying the induction of hepatic MRP3 expression and function by omeprazole.

Pan YQ, Mi QY, He BS, Zhao SL, Tai T, Xie HG. Pan YQ, et al. Among authors: xie hg. Biopharm Drug Dispos. 2015 May;36(4):232-44. doi: 10.1002/bdd.1936. Epub 2015 Feb 11. Biopharm Drug Dispos. 2015. PMID: 25597959

6

Enhanced Platelet Response to Clopidogrel in Abcc3-deficient Mice Due to Its Increased Bioactivation.

Tai T, Mi QY, Ji JZ, Yin Q, Pan YQ, Zhang MR, Huang BB, Xie HG. Tai T, et al. Among authors: xie hg. J Cardiovasc Pharmacol. 2016 Dec;68(6):433-440. doi: 10.1097/FJC.0000000000000428. J Cardiovasc Pharmacol. 2016. PMID: 27525577

7

Overcoming Clopidogrel Resistance: Three Promising Novel Antiplatelet Drugs Developed in China.

Xie HG, Jia YM, Tai T, Ji JZ. Xie HG, et al. J Cardiovasc Pharmacol. 2017 Dec;70(6):356-361. doi: 10.1097/FJC.0000000000000529. J Cardiovasc Pharmacol. 2017. PMID: 28817486 Review.

8

Mrp3 Transports Clopidogrel Acyl Glucuronide from the Hepatocytes into Blood.

Ji JZ, Tai T, Huang BB, Gu TT, Mi QY, Xie HG. Ji JZ, et al. Among authors: xie hg. Drug Metab Dispos. 2018 Feb;46(2):151-154. doi: 10.1124/dmd.117.078329. Epub 2017 Dec 1. Drug Metab Dispos. 2018. PMID: 29196299

9

Human UGT2B7 is the major isoform responsible for the glucuronidation of clopidogrel carboxylate.

Ji JZ, Huang BB, Gu TT, Tai T, Zhou H, Jia YM, Mi QY, Zhang MR, Xie HG. Ji JZ, et al. Among authors: xie hg. Biopharm Drug Dispos. 2018 Feb;39(2):88-98. doi: 10.1002/bdd.2117. Epub 2018 Jan 9. Biopharm Drug Dispos. 2018. PMID: 29240983

10

Aspirin Attenuates the Bioactivation of and Platelet Response to Vicagrel in Mice.

Jia YM, Gu TT, Ji JZ, Tai T, Zhang MR, Huang BB, Zhou H, Mi QY, Xie HG. Jia YM, et al. Among authors: xie hg. J Cardiovasc Pharmacol. 2018 Nov;72(5):252-258. doi: 10.1097/FJC.0000000000000622. J Cardiovasc Pharmacol. 2018. PMID: 30358688

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