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How the liver transcriptome and lipid composition influence the progression of nonalcoholic fatty liver disease to hepatocellular carcinoma in a murine model.
Leopold M, Mass-Sanchez PB, Krizanac M, Štancl P, Karlić R, Prabutzki P, Parafianczuk V, Schiller J, Asimakopoulos A, Engel KM, Weiskirchen R. Leopold M, et al. Among authors: krizanac m. Biochim Biophys Acta Mol Cell Biol Lipids. 2025 Jan;1870(1):159574. doi: 10.1016/j.bbalip.2024.159574. Epub 2024 Nov 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2025. PMID: 39510374 Free article.
The influence of perilipin 5 deficiency on gut microbiome profiles in murine metabolic dysfunction-associated fatty liver disease (MAFLD) and MAFLD-hepatocellular carcinoma.
Krizanac M, Štancl P, Mass-Sanchez PB, Karlić R, Moeckel D, Lammers T, Asimakopoulos A, Weiskirchen R. Krizanac M, et al. Front Cell Infect Microbiol. 2024 Oct 14;14:1443654. doi: 10.3389/fcimb.2024.1443654. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 39469452 Free PMC article.
Perilipin 5 deletion protects against nonalcoholic fatty liver disease and hepatocellular carcinoma by modulating lipid metabolism and inflammatory responses.
Mass-Sanchez PB, Krizanac M, Štancl P, Leopold M, Engel KM, Buhl EM, van Helden J, Gassler N, Schiller J, Karlić R, Möckel D, Lammers T, Meurer SK, Weiskirchen R, Asimakopoulos A. Mass-Sanchez PB, et al. Among authors: krizanac m. Cell Death Discov. 2024 Feb 22;10(1):94. doi: 10.1038/s41420-024-01860-4. Cell Death Discov. 2024. PMID: 38388533 Free PMC article.
The Interplay of TGF-β1 and Cholesterol Orchestrating Hepatocyte Cell Fate, EMT, and Signals for HSC Activation.
Wang S, Link F, Han M, Chaudhary R, Asimakopoulos A, Liebe R, Yao Y, Hammad S, Dropmann A, Krizanac M, Rubie C, Feiner LK, Glanemann M, Ebert MPA, Weiskirchen R, Henis YI, Ehrlich M, Dooley S. Wang S, et al. Among authors: krizanac m. Cell Mol Gastroenterol Hepatol. 2024;17(4):567-587. doi: 10.1016/j.jcmgh.2023.12.012. Epub 2023 Dec 27. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38154598 Free PMC article.