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Page 1
FLT3 signaling inhibition abrogates opioid tolerance and hyperalgesia while preserving analgesia.
Jouvenel A, Tassou A, Thouaye M, Ruel J, Antri M, Leyris JP, Giraudin A, Mallié S, Sar C, Diouloufet L, Sonrier C, Daubeuf F, Bertin J, Alves S, Ventéo S, Frossard N, Carroll P, Mechaly I, Rognan D, Sokoloff P, Dallel R, Delmas P, Valmier J, Rivat C. Jouvenel A, et al. Among authors: rognan d. Nat Commun. 2024 Nov 7;15(1):9633. doi: 10.1038/s41467-024-54054-y. Nat Commun. 2024. PMID: 39511220 Free PMC article.
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.
Rivat C, Sar C, Mechaly I, Leyris JP, Diouloufet L, Sonrier C, Philipson Y, Lucas O, Mallié S, Jouvenel A, Tassou A, Haton H, Venteo S, Pin JP, Trinquet E, Charrier-Savournin F, Mezghrani A, Joly W, Mion J, Schmitt M, Pattyn A, Marmigère F, Sokoloff P, Carroll P, Rognan D, Valmier J. Rivat C, et al. Among authors: rognan d. Nat Commun. 2018 Mar 12;9(1):1042. doi: 10.1038/s41467-018-03496-2. Nat Commun. 2018. PMID: 29531216 Free PMC article.
High-Throughput Screening for Extracellular Inhibitors of the FLT3 Receptor Tyrosine Kinase Reveals Chemically Diverse and Druggable Negative Allosteric Modulators.
Hany R, Leyris JP, Bret G, Mallié S, Sar C, Thouaye M, Hamze A, Provot O, Sokoloff P, Valmier J, Villa P, Rognan D. Hany R, et al. Among authors: rognan d. ACS Chem Biol. 2022 Mar 18;17(3):709-722. doi: 10.1021/acschembio.2c00048. Epub 2022 Feb 28. ACS Chem Biol. 2022. PMID: 35227060 Free article.
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Bollenbach M, Nemska S, Wagner P, Camelin G, Daubeuf F, Obrecht A, Villa P, Rognan D, Bihel F, Bourguignon JJ, Schmitt M, Frossard N. Bollenbach M, et al. Among authors: rognan d. Molecules. 2021 Jan 13;26(2):391. doi: 10.3390/molecules26020391. Molecules. 2021. PMID: 33450992 Free PMC article.
Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.
Regenass P, Abboud D, Daubeuf F, Lehalle C, Gizzi P, Riché S, Hachet-Haas M, Rohmer F, Gasparik V, Boeglin D, Haiech J, Knehans T, Rognan D, Heissler D, Marsol C, Villa P, Galzi JL, Hibert M, Frossard N, Bonnet D. Regenass P, et al. Among authors: rognan d. J Med Chem. 2018 Sep 13;61(17):7671-7686. doi: 10.1021/acs.jmedchem.8b00657. Epub 2018 Aug 28. J Med Chem. 2018. PMID: 30106292
Estimating the Similarity between Protein Pockets.
Eguida M, Rognan D. Eguida M, et al. Among authors: rognan d. Int J Mol Sci. 2022 Oct 18;23(20):12462. doi: 10.3390/ijms232012462. Int J Mol Sci. 2022. PMID: 36293316 Free PMC article. Review.
157 results