Krenske EH - Search Results

1

Loss of fluorine during crosslinking by the biarylitide P450_Blt proceeds due to restricted peptide orientation.

Zhao Y, Gullick J, Hansen MH, Coe L, Treisman M, Schittenhelm RB, McKay A, Murray LAM, Tailhades J, De Voss JJ, Krenske EH, Cryle MJ. Zhao Y, et al. Among authors: krenske eh. Chem Commun (Camb). 2024 Nov 21;60(94):13951-13954. doi: 10.1039/d4cc04092a. Chem Commun (Camb). 2024. PMID: 39512132

2

Direct Observation of an Oxepin from a Bacterial Cytochrome P450-Catalyzed Oxidation.

Stok JE, Chow S, Krenske EH, Farfan Soto C, Matyas C, Poirier RA, Williams CM, De Voss JJ. Stok JE, et al. Among authors: krenske eh. Chemistry. 2016 Mar 18;22(13):4408-12. doi: 10.1002/chem.201600246. Epub 2016 Feb 16. Chemistry. 2016. PMID: 26811874

3

Biosynthetic insights provided by unusual sesterterpenes from the medicinal herb Aletris farinosa.

Challinor VL, Johnston RC, Bernhardt PV, Lehmann RP, Krenske EH, De Voss JJ. Challinor VL, et al. Among authors: krenske eh. Chem Sci. 2015 Oct 1;6(10):5740-5745. doi: 10.1039/c5sc02056e. Epub 2015 Jul 6. Chem Sci. 2015. PMID: 29081941 Free PMC article.

4

Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics.

Greule A, Izoré T, Iftime D, Tailhades J, Schoppet M, Zhao Y, Peschke M, Ahmed I, Kulik A, Adamek M, Goode RJA, Schittenhelm RB, Kaczmarski JA, Jackson CJ, Ziemert N, Krenske EH, De Voss JJ, Stegmann E, Cryle MJ. Greule A, et al. Among authors: krenske eh. Nat Commun. 2019 Jun 13;10(1):2613. doi: 10.1038/s41467-019-10384-w. Nat Commun. 2019. PMID: 31197182 Free PMC article.

5

Rearrangement-Free Hydroxylation of Methylcubanes by a Cytochrome P450: The Case for Dynamical Coupling of C-H Abstraction and Rebound.

Sarkar MR, Houston SD, Savage GP, Williams CM, Krenske EH, Bell SG, De Voss JJ. Sarkar MR, et al. Among authors: krenske eh. J Am Chem Soc. 2019 Dec 18;141(50):19688-19699. doi: 10.1021/jacs.9b08064. Epub 2019 Dec 6. J Am Chem Soc. 2019. PMID: 31739667

6

Why do silanes reduce electron-rich phosphine oxides faster than electron-poor phosphine oxides?

Kirk AM , O'Brien CJ , Krenske EH . Kirk AM , et al. Among authors: krenske eh. Chem Commun (Camb). 2020 Jan 28;56(8):1227-1230. doi: 10.1039/c9cc08718d. Chem Commun (Camb). 2020. PMID: 31897455

7

Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.

Izoré T, Candace Ho YT, Kaczmarski JA, Gavriilidou A, Chow KH, Steer DL, Goode RJA, Schittenhelm RB, Tailhades J, Tosin M, Challis GL, Krenske EH, Ziemert N, Jackson CJ, Cryle MJ. Izoré T, et al. Among authors: krenske eh. Nat Commun. 2021 May 4;12(1):2511. doi: 10.1038/s41467-021-22623-0. Nat Commun. 2021. PMID: 33947858 Free PMC article.

8

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.

Coleman T, Lee JZH, Kirk AM, Doherty DZ, Podgorski MN, Pinidiya DK, Bruning JB, De Voss JJ, Krenske EH, Bell SG. Coleman T, et al. Among authors: krenske eh. Chemistry. 2022 Dec 1;28(67):e202201895. doi: 10.1002/chem.202201895. Epub 2022 Oct 6. Chemistry. 2022. PMID: 36043399 Free PMC article.

9

Croton insularis introduces the seco-casbane class with EBC-329 and the first casbane endoperoxide EBC-324.

Maslovskaya LA, Savchenko AI, Krenske EH, Gordon VA, Reddell PW, Pierce CJ, Parsons PG, Williams CM. Maslovskaya LA, et al. Among authors: krenske eh. Chem Commun (Camb). 2014 Oct 21;50(82):12315-7. doi: 10.1039/c4cc05413j. Chem Commun (Camb). 2014. PMID: 25178400

10

Hyperstable alkenes: are they remarkably unreactive?

Summersgill MD, Gahan LR, Chow S, Pierens GK, Bernhardt PV, Krenske EH, Williams CM. Summersgill MD, et al. Among authors: krenske eh. Chem Sci. 2024 Nov 5;15(46):19299-19306. doi: 10.1039/d4sc06697a. eCollection 2024 Nov 27. Chem Sci. 2024. PMID: 39568885 Free PMC article.

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