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Page 1
IL1RAP Blockade With a Monoclonal Antibody Reduces Cardiac Inflammation and Preserves Heart Function in Viral and Autoimmune Myocarditis.
Lema DA, Jakobsson G, Daoud A, Elias D, Talor MV, Rattik S, Grönberg C, Kalinoski H, Jaensson Gyllenbäck E, Wang N, Liberg D, Schiopu A, Čiháková D. Lema DA, et al. Among authors: jaensson gyllenback e. Circ Heart Fail. 2024 Dec;17(12):e011729. doi: 10.1161/CIRCHEARTFAILURE.124.011729. Epub 2024 Nov 8. Circ Heart Fail. 2024. PMID: 39513273 Free PMC article.
Blockade of IL-1α and IL-1β signaling by the anti-IL1RAP antibody nadunolimab (CAN04) mediates synergistic anti-tumor efficacy with chemotherapy.
Rydberg Millrud C, Deronic A, Grönberg C, Jaensson Gyllenbäck E, von Wachenfeldt K, Forsberg G, Liberg D. Rydberg Millrud C, et al. Among authors: jaensson gyllenback e. Cancer Immunol Immunother. 2023 Mar;72(3):667-678. doi: 10.1007/s00262-022-03277-3. Epub 2022 Aug 29. Cancer Immunol Immunother. 2023. PMID: 36036818 Free PMC article.
Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation.
Mulholland M, Depuydt MAC, Jakobsson G, Ljungcrantz I, Grentzmann A, To F, Bengtsson E, Jaensson Gyllenbäck E, Grönberg C, Rattik S, Liberg D, Schiopu A, Björkbacka H, Kuiper J, Bot I, Slütter B, Engelbertsen D. Mulholland M, et al. Among authors: jaensson gyllenback e. Cardiovasc Res. 2024 May 7;120(6):581-595. doi: 10.1093/cvr/cvae046. Cardiovasc Res. 2024. PMID: 38563353 Free PMC article.