Maamra M - Search Results

1

An Experimental and Modeling Approach to Study Tangential Flow Filtration Performance for mRNA Drug Substance Purification.

Nourafkan E, Kenyon C, Nair A, Loveday KA, Welbourne EN, Tao M, Ahmed M, Middleton J, Dickman MJ, Brown SF, Maamra M, Cordiner J, Kis Z. Nourafkan E, et al. Among authors: maamra m. Biotechnol J. 2024 Nov;19(11):e202400473. doi: 10.1002/biot.202400473. Biotechnol J. 2024. PMID: 39513347

2

Quality by design for mRNA platform purification based on continuous oligo-dT chromatography.

Qu J, Nair A, Muir GW, Loveday KA, Yang Z, Nourafkan E, Welbourne EN, Maamra M, Dickman MJ, Kis Z. Qu J, et al. Among authors: maamra m. Mol Ther Nucleic Acids. 2024 Sep 11;35(4):102333. doi: 10.1016/j.omtn.2024.102333. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39380714 Free PMC article.

3

The effect of TG2-inhibitory monoclonal antibody zampilimab on tissue fibrosis in human in vitro and primate in vivo models of chronic kidney disease.

Huang L, Bon H, Maamra M, Holmes T, Atkinson J, Cain K, Kennedy J, Kettleborough C, Matthews D, Twomey B, Ni J, Song Z, Watson PF, Johnson TS. Huang L, et al. Among authors: maamra m. PLoS One. 2024 May 16;19(5):e0298864. doi: 10.1371/journal.pone.0298864. eCollection 2024. PLoS One. 2024. PMID: 38753630 Free PMC article.

4

Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling.

Maamra M, Benayad OM, Matthews D, Kettleborough C, Atkinson J, Cain K, Bon H, Brand H, Parkinson M, Watson PF, Johnson TS. Maamra M, et al. Br J Pharmacol. 2022 Jun;179(11):2697-2712. doi: 10.1111/bph.15774. Epub 2022 Apr 5. Br J Pharmacol. 2022. PMID: 34879432 Free article.

5

Integration of Transcriptome and Metabolome Provides Unique Insights to Pathways Associated With Obese Breast Cancer Patients.

Hassan MA, Al-Sakkaf K, Shait Mohammed MR, Dallol A, Al-Maghrabi J, Aldahlawi A, Ashoor S, Maamra M, Ragoussis J, Wu W, Khan MI, Al-Malki AL, Choudhry H. Hassan MA, et al. Among authors: maamra m. Front Oncol. 2020 May 19;10:804. doi: 10.3389/fonc.2020.00804. eCollection 2020. Front Oncol. 2020. PMID: 32509585 Free PMC article.

6

Interplay between transglutaminases and heparan sulphate in progressive renal scarring.

Burhan I, Furini G, Lortat-Jacob H, Atobatele AG, Scarpellini A, Schroeder N, Atkinson J, Maamra M, Nutter FH, Watson P, Vinciguerra M, Johnson TS, Verderio EA. Burhan I, et al. Among authors: maamra m. Sci Rep. 2016 Oct 3;6:31343. doi: 10.1038/srep31343. Sci Rep. 2016. PMID: 27694984 Free PMC article.

7

Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody.

Carpenter B, Hemsworth GR, Wu Z, Maamra M, Strasburger CJ, Ross RJ, Artymiuk PJ. Carpenter B, et al. Among authors: maamra m. Structure. 2012 Mar 7;20(3):487-97. doi: 10.1016/j.str.2012.01.019. Structure. 2012. PMID: 22405007 Free article.

8

Identification of a monoclonal antibody against the leptin receptor that acts as an antagonist and blocks human monocyte and T cell activation.

Fazeli M, Zarkesh-Esfahani H, Wu Z, Maamra M, Bidlingmaier M, Pockley AG, Watson P, Matarese G, Strasburger CJ, Ross RJ. Fazeli M, et al. Among authors: maamra m. J Immunol Methods. 2006 May 30;312(1-2):190-200. doi: 10.1016/j.jim.2006.03.011. Epub 2006 Apr 27. J Immunol Methods. 2006. PMID: 16690078

9

A 36 residues insertion in the dimerization domain of the growth hormone receptor results in defective trafficking rather than impaired signaling.

Maamra M, Milward A, Esfahani HZ, Abbott LP, Metherell LA, Savage MO, Clark AJ, Ross RJ. Maamra M, et al. J Endocrinol. 2006 Feb;188(2):251-61. doi: 10.1677/joe.1.06252. J Endocrinol. 2006. PMID: 16461551

10

Pegvisomant, a growth hormone-specific antagonist, undergoes cellular internalization.

Maamra M, Kopchick JJ, Strasburger CJ, Ross RJ. Maamra M, et al. J Clin Endocrinol Metab. 2004 Sep;89(9):4532-7. doi: 10.1210/jc.2003-031781. J Clin Endocrinol Metab. 2004. PMID: 15356058

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