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Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults.
Samarelli F, Purgatorio R, Lopopolo G, Deruvo C, Catto M, Andresini M, Carrieri A, Nicolotti O, De Palma A, Miniero DV, de Candia M, Altomare CD. Samarelli F, et al. Among authors: miniero dv. Eur J Med Chem. 2024 Apr 15;270:116353. doi: 10.1016/j.ejmech.2024.116353. Epub 2024 Mar 20. Eur J Med Chem. 2024. PMID: 38579622 Free article.
Mannich base approach to 5-methoxyisatin 3-(4-isopropylphenyl)hydrazone: A water-soluble prodrug for a multitarget inhibition of cholinesterases, beta-amyloid fibrillization and oligomer-induced cytotoxicity.
Pisani L, De Palma A, Giangregorio N, Miniero DV, Pesce P, Nicolotti O, Campagna F, Altomare CD, Catto M. Pisani L, et al. Among authors: miniero dv. Eur J Pharm Sci. 2017 Nov 15;109:381-388. doi: 10.1016/j.ejps.2017.08.004. Epub 2017 Aug 9. Eur J Pharm Sci. 2017. PMID: 28801274
hERG stereoselective modulation by mexiletine-derived ureas: Molecular docking study, synthesis, and biological evaluation.
Milani G, Budriesi R, Tavazzani E, Cavalluzzi MM, Mattioli LB, Miniero DV, Delre P, Belviso BD, Denegri M, Cuocci C, Rotondo NP, De Palma A, Gualdani R, Caliandro R, Mangiatordi GF, Kumawat A, Camilloni C, Priori S, Lentini G. Milani G, et al. Among authors: miniero dv. Arch Pharm (Weinheim). 2023 Oct;356(10):e2300116. doi: 10.1002/ardp.202300116. Epub 2023 Jul 17. Arch Pharm (Weinheim). 2023. PMID: 37460390 Free article.
34 results