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Evaluation of UCP1162, a potent propargyl-linked inhibitor of dihydrofolate reductase with potential application to cancer and autoimmune disease.
Ozcan Tezgin D, Kurkcu S, Si D, Krucinska J, Mosley A, Mehta P, Babic I, Nurmemmedov E, Kuo A, He W, Nelson CE, Wright L, Wright DL, Giardina C. Ozcan Tezgin D, et al. Among authors: nelson ce. Biochem Pharmacol. 2024 Nov 9;230(Pt 3):116617. doi: 10.1016/j.bcp.2024.116617. Online ahead of print. Biochem Pharmacol. 2024. PMID: 39528074
Experimental coral reef communities transform yet persist under mitigated future ocean warming and acidification.
Jury CP, Bahr KD, Cros A, Dobson KL, Freel EB, Graham AT, McLachlan RH, Nelson CE, Price JT, Rocha de Souza M, Shizuru L, Smith CM, Sparagon WJ, Squair CA, Timmers MA, Vicente J, Webb MK, Yamase NH, Grottoli AG, Toonen RJ. Jury CP, et al. Among authors: nelson ce. Proc Natl Acad Sci U S A. 2024 Nov 5;121(45):e2407112121. doi: 10.1073/pnas.2407112121. Epub 2024 Oct 29. Proc Natl Acad Sci U S A. 2024. PMID: 39471225 Free PMC article.
SARS-CoV-2 infection perturbs the gastrointestinal tract and induces modest microbial translocation across the intestinal barrier.
Brooks K, Nelson CE, Aguilar C, Hoang TN, Ortiz AM, Langner CA, Yee DS, Flynn JK, Vrba S, Laidlaw E, Vannella KM, Grazioli A, Saharia KK, Purcell M, Singireddy S, Wu J, Stankiewicz J, Chertow DS, Sereti I, Paiardini M, Hickman HD, Via LE, Barber DL, Brenchley JM. Brooks K, et al. Among authors: nelson ce. J Virol. 2024 Oct 22;98(10):e0128824. doi: 10.1128/jvi.01288-24. Epub 2024 Sep 12. J Virol. 2024. PMID: 39264207 Free PMC article.
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques.
Nelson CE, Foreman TW, Fukutani ER, Kauffman KD, Sakai S, Fleegle JD, Gomez F; NIAID/DIR Tuberculosis Imaging Program; Gould ST, Le Nouën C, Liu X, Burdette TL, Garza NL, Lafont BAP, Brooks K, Lindestam Arlehamn CS, Weiskopf D, Sette A, Hickman HD, Buchholz UJ, Johnson RF, Brenchley JM, Oberman JP, Quieroz ATL, Andrade BB, Via LE, Barber DL. Nelson CE, et al. PLoS Pathog. 2024 Jul 1;20(7):e1012339. doi: 10.1371/journal.ppat.1012339. eCollection 2024 Jul. PLoS Pathog. 2024. PMID: 38950078 Free PMC article.
Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques.
Kaiser JA, Nelson CE, Liu X, Park HS, Matsuoka Y, Luongo C, Santos C, Ahlers LRH, Herbert R, Moore IN, Wilder-Kofie T, Moore R, Walker A, Yang L, Munir S, Teng IT, Kwong PD, Dowdell K, Nguyen H, Kim J, Cohen JI, Johnson RF, Garza NL, Via LE, Barber DL, Buchholz UJ, Le Nouën C. Kaiser JA, et al. Among authors: nelson ce. Nat Commun. 2024 Apr 26;15(1):3553. doi: 10.1038/s41467-024-47784-6. Nat Commun. 2024. PMID: 38670948 Free PMC article.
247 results