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Page 1
Astrocyte transcriptomic changes along the spatiotemporal progression of Alzheimer's disease.
Serrano-Pozo A, Li H, Li Z, Muñoz-Castro C, Jaisa-Aad M, Healey MA, Welikovitch LA, Jayakumar R, Bryant AG, Noori A, Connors TR, Hu M, Zhao K, Liao F, Lin G, Pastika T, Tamm J, Abdourahman A, Kwon T, Bennett RE, Woodbury ME, Wachter A, Talanian RV, Biber K, Karran EH, Hyman BT, Das S. Serrano-Pozo A, et al. Among authors: talanian rv. Nat Neurosci. 2024 Dec;27(12):2384-2400. doi: 10.1038/s41593-024-01791-4. Epub 2024 Nov 11. Nat Neurosci. 2024. PMID: 39528672 Free PMC article.
Distinct Transcriptomic Responses to Aβ plaques, Neurofibrillary Tangles, and APOE in Alzheimer's Disease.
Das S, Li Z, Wachter A, Alla S, Noori A, Abdourahman A, Tamm JA, Woodbury ME, Talanian RV, Biber K, Karran EH, Hyman BT, Serrano-Pozo A. Das S, et al. Among authors: talanian rv. bioRxiv [Preprint]. 2023 Mar 21:2023.03.20.533303. doi: 10.1101/2023.03.20.533303. bioRxiv. 2023. Update in: Alzheimers Dement. 2024 Jan;20(1):74-90. doi: 10.1002/alz.13387 PMID: 36993332 Free PMC article. Updated. Preprint.
Landscape of brain myeloid cell transcriptome along the spatiotemporal progression of Alzheimer's disease reveals distinct sequential responses to Aβ and tau.
Wachter A, Woodbury ME, Lombardo S, Abdourahman A, Wuest C, McGlame E, Pastika T, Tamm J, Romanul N, Yanamandra K, Bennett R, Lin G, Kwon T, Liao F, Klein C, Grinberg Y, Jaisa-Aad M, Li H, Frosch MP, Kummer MP, Das S, Dellovade T, Karran EH, Langlois X, Ried JS, Serrano-Pozo A, Talanian RV, Biber K, Hyman BT. Wachter A, et al. Among authors: talanian rv. Acta Neuropathol. 2024 Apr 1;147(1):65. doi: 10.1007/s00401-024-02704-2. Acta Neuropathol. 2024. PMID: 38557897 Free PMC article.
Endothelial Cells are Heterogeneous in Different Brain Regions and are Dramatically Altered in Alzheimer's Disease.
Bryant A, Li Z, Jayakumar R, Serrano-Pozo A, Woost B, Hu M, Woodbury ME, Wachter A, Lin G, Kwon T, Talanian RV, Biber K, Karran EH, Hyman BT, Das S, Bennett R. Bryant A, et al. Among authors: talanian rv. bioRxiv [Preprint]. 2023 Feb 16:2023.02.16.528825. doi: 10.1101/2023.02.16.528825. bioRxiv. 2023. Update in: J Neurosci. 2023 Jun 14;43(24):4541-4557. doi: 10.1523/JNEUROSCI.0237-23.2023 PMID: 36824974 Free PMC article. Updated. Preprint.
Endothelial Cells Are Heterogeneous in Different Brain Regions and Are Dramatically Altered in Alzheimer's Disease.
Bryant A, Li Z, Jayakumar R, Serrano-Pozo A, Woost B, Hu M, Woodbury ME, Wachter A, Lin G, Kwon T, Talanian RV, Biber K, Karran EH, Hyman BT, Das S, Bennett RE. Bryant A, et al. Among authors: talanian rv. J Neurosci. 2023 Jun 14;43(24):4541-4557. doi: 10.1523/JNEUROSCI.0237-23.2023. Epub 2023 May 19. J Neurosci. 2023. PMID: 37208174 Free PMC article.
MEK1/2 activity modulates TREM2 cell surface recruitment.
Schapansky J, Grinberg YY, Osiecki DM, Freeman EA, Walker SG, Karran E, Gopalakrishnan SM, Talanian RV. Schapansky J, et al. Among authors: talanian rv. J Biol Chem. 2021 Jan-Jun;296:100218. doi: 10.1074/jbc.RA120.014352. Epub 2020 Dec 25. J Biol Chem. 2021. PMID: 33839686 Free PMC article.
Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.
Argiriadi MA, Goedken ER, Banach D, Borhani DW, Burchat A, Dixon RW, Marcotte D, Overmeyer G, Pivorunas V, Sadhukhan R, Sousa S, Moore NS, Tomlinson M, Voss J, Wang L, Wishart N, Woller K, Talanian RV. Argiriadi MA, et al. Among authors: talanian rv. BMC Struct Biol. 2012 Sep 20;12:22. doi: 10.1186/1472-6807-12-22. BMC Struct Biol. 2012. PMID: 22995073 Free PMC article.
53 results