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Molecular docking and antibacterial and antibiotic-modifying activities of synthetic chalcone (2E)-1-(3'-aminophenyl)-3-(4-dimethylaminophenyl)-prop-2-en-1-one in a MepA efflux pump-expressing Staphylococcus aureus strain.
da Silva L, Gonçalves CAC, Bezerra AH, Dos Santos Barbosa CR, Rocha JE, de Matos YMLS, de Oliveira LCC, Dos Santos HS, Coutinho HDM, da Cunha FAB. da Silva L, et al. Among authors: de oliveira lcc. Folia Microbiol (Praha). 2024 Nov 12. doi: 10.1007/s12223-024-01221-9. Online ahead of print. Folia Microbiol (Praha). 2024. PMID: 39531148
Synthesis, spectroscopic characterization, and antibacterial activity of chalcone (2E)-1-(3'-aminophenyl)-3-(4-dimethylaminophenyl)-prop-2-en-1-one against multiresistant Staphylococcus aureus carrier of efflux pump mechanisms and β-lactamase.
da Silva L, Donato IA, Bezerra SR, Dos Santos HS, Bandeira PN, do Nascimento MTR, Guedes JM, Freitas PR, de Araújo ACJ, de Freitas TS, Coutinho HDM, de Matos YMLS, de Oliveira LCC, da Cunha FAB. da Silva L, et al. Among authors: de oliveira lcc. Fundam Clin Pharmacol. 2024 Feb;38(1):60-71. doi: 10.1111/fcp.12938. Epub 2023 Jul 27. Fundam Clin Pharmacol. 2024. PMID: 37497790
Evaluation of isoeugenol in inhibition of Staphylococcus aureus efflux pumps and their toxicity using Drosophila melanogaster model.
de Sousa Júnior DL, Cordeiro PPM, Dos Santos Barbosa CR, Muniz DF, de Sousa Silveira Z, Macêdo NS, de Lacerda Neto LJ, de Freitas TS, Dos Santos JFS, Coutinho HDM, de Oliveira LCC, da Cunha FAB. de Sousa Júnior DL, et al. Among authors: de oliveira lcc. Life Sci. 2021 Nov 15;285:119940. doi: 10.1016/j.lfs.2021.119940. Epub 2021 Sep 9. Life Sci. 2021. PMID: 34508763