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Page 1
Mutant PP2A Induces IGFBP2 Secretion to Promote Development of High-Grade Uterine Cancer.
Haanen TJ, Boock S, Callahan CG, Peris I, Zawacki KP, Raines B, Nino CA, Tran B, Harold A, Hodges Onishi G, Hinderman M, Dowdican A, Huang W, Taylor DJ, Taylor SE, Jackson MW, DiFeo A, O'Connor CM, Narla G. Haanen TJ, et al. Among authors: difeo a. Cancer Res. 2024 Nov 12. doi: 10.1158/0008-5472.CAN-24-1263. Online ahead of print. Cancer Res. 2024. PMID: 39531506
Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote Ovarian Cancer Malignancy.
Horst EN, Cotter LR, Bonini M, Novak CM, Treacher NM, Zhang Y, Jackson ZF, Narayanan IV, Fischer ZS, Sunshine AR, Lin Z, Tran LA, Ljungman M, Maturen KE, DiFeo A, Nordsletten DA, Mehta G. Horst EN, et al. Among authors: difeo a. Res Sq [Preprint]. 2024 Oct 15:rs.3.rs-5160301. doi: 10.21203/rs.3.rs-5160301/v1. Res Sq. 2024. PMID: 39483899 Free PMC article. Preprint.
Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-Damage-Sensing-Dependent Cell Protection.
Centeno D, Farsinejad S, Kochetkova E, Volpari T, Gladych-Macioszek A, Klupczynska-Gabryszak A, Polotaye T, Greenberg M, Kung D, Hyde E, Alshehri S, Pavlovic T, Sullivan W, Plewa S, Vakifahmetoglu-Norberg H, Monsma FJ Jr, Muller PAJ, Matysiak J, Zaborowski MP, DiFeo A, Norberg E, Martin LA, Iwanicki M. Centeno D, et al. Among authors: difeo a. Nutrients. 2024 Jun 9;16(12):1816. doi: 10.3390/nu16121816. Nutrients. 2024. PMID: 38931171 Free PMC article.
Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway.
Avelar RA, Gupta R, Carvette G, da Veiga Leprevost F, Colina J, Teitel J, Nesvizhskii AI, O'Connor CM, Hatzoglou M, Shenolikar S, Arvan P, Narla G, DiFeo A. Avelar RA, et al. Among authors: difeo a. Res Sq [Preprint]. 2024 Mar 28:rs.3.rs-4013396. doi: 10.21203/rs.3.rs-4013396/v1. Res Sq. 2024. Update in: Cell Death Differ. 2024 Sep 30. doi: 10.1038/s41418-024-01378-3. PMID: 38585734 Free PMC article. Updated. Preprint.
Cooperativity of c-MYC with Krüppel-Like Factor 6 Splice Variant 1 induces phenotypic plasticity and promotes prostate cancer progression and metastasis.
Izadmehr S, Fernandez-Hernandez H, Wiredja D, Kirschenbaum A, Lee-Poturalski C, Tavassoli P, Yao S, Schlatzer D, Hoon D, Difeo A, Levine AC, Mosquera JM, Galsky MD, Cordon-Cardo C, Narla G. Izadmehr S, et al. Among authors: difeo a. bioRxiv [Preprint]. 2024 Feb 1:2024.01.30.577982. doi: 10.1101/2024.01.30.577982. bioRxiv. 2024. PMID: 38352401 Free PMC article. Preprint.
Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-damage-sensing-dependent Cell Protection.
Centeno D, Farsinejad S, Kochetkova E, Volpari T, Gladych-Macioszek A, Klupczynska-Gabryszak A, Polotaye T, Greenberg M, Kung D, Hyde E, Alshehri S, Pavlovic T, Sullivan W, Plewa S, Vakifahmetoglu-Norberg H, Monsma FJ, Muller PAJ, Matysiak J, Zaborowski M, DiFeo A, Norberg E, Martin LA, Iwanicki M. Centeno D, et al. Among authors: difeo a. bioRxiv [Preprint]. 2024 May 14:2023.02.24.529893. doi: 10.1101/2023.02.24.529893. bioRxiv. 2024. Update in: Nutrients. 2024 Jun 09;16(12):1816. doi: 10.3390/nu16121816. PMID: 36909636 Free PMC article. Updated. Preprint.
Small-Molecule-Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death.
Avelar RA, Armstrong AJ, Carvette G, Gupta R, Puleo N, Colina JA, Joseph P, Sobeck AM, O'Connor CM, Raines B, Gandhi A, Dziubinski ML, Ma DS, Resnick K, Singh S, Zanotti K, Nagel C, Waggoner S, Thomas DG, Skala SL, Zhang J, Narla G, DiFeo A. Avelar RA, et al. Among authors: difeo a. Mol Cancer Ther. 2023 May 4;22(5):599-615. doi: 10.1158/1535-7163.MCT-21-0880. Mol Cancer Ther. 2023. PMID: 36788429 Free PMC article.
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.
Achreja A, Yu T, Mittal A, Choppara S, Animasahun O, Nenwani M, Wuchu F, Meurs N, Mohan A, Jeon JH, Sarangi I, Jayaraman A, Owen S, Kulkarni R, Cusato M, Weinberg F, Kweon HK, Subramanian C, Wicha MS, Merajver SD, Nagrath S, Cho KR, DiFeo A, Lu X, Nagrath D. Achreja A, et al. Among authors: difeo a. Nat Metab. 2022 Sep;4(9):1119-1137. doi: 10.1038/s42255-022-00636-3. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131208
80 results